Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer (Q28854605)

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer (English)

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

GOA release 2020-03-11

purine-specific mismatch base pair DNA N-glycosylase activity

1 reference

GOA release 2020-03-11

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Yusaku Nakabeppu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Masanori Goto

1

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Hong Tao

4

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Hidetaka Yamada

5

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Toshihiro Tsuneyoshi

6

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Haruhiko Sugimura

7

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

publication date

1 November 2010

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

31

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

11

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

E1861-74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

A method and server for predicting damaging missense mutations

14 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Altered expression of the human base excision repair gene NTH1 in gastric cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Characterization of mutant MUTYH proteins associated with familial colorectal cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Hereditary colorectal cancer syndromes: molecular genetics, genetic counseling, diagnosis and management.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

MUTYH-associated polyposis--from defect in base excision repair to clinical genetic testing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Expanded extracolonic tumor spectrum in MUTYH-associated polyposis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Increased frequency of disease-causing MYH mutations in colon cancer families.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Novel findings in Swedish patients with MYH-associated polyposis: mutation detection and clinical characterization.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Standardizing mutation nomenclature: why bother?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051265

Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20848659

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20848659

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20848659

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

2 references

28 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848659%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

2 references

28 February 2017