Structural basis for a major histocompatibility complex class Ib-restricted T cell response (Q28941762)

GOA release 2020-03-11

Travis Beddoe

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James McCluskey

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James McCluskey

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Jamie Rossjohn

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Jamie Rossjohn

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author name string

Hilary L. Hoare

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14 March 2017

Lucy C. Sullivan

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14 March 2017

Gabriella Pietra

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14 March 2017

Craig S. Clements

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14 March 2017

Eleanor J. Lee

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14 March 2017

Lauren K. Ely

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14 March 2017

Michela Falco

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14 March 2017

Lars Kjer-Nielsen

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14 March 2017

Hugh H. Reid

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14 March 2017

Lorenzo Moretta

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14 March 2017

Andrew G. Brooks

CD8 T cell responses to infectious pathogens.

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14 March 2017

language of work or name

English

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publication date

1 March 2006

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14 March 2017

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14 March 2017

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14 March 2017

256–264

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14 March 2017

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14 March 2017

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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

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Species-specific evolution of MHC class I genes in the higher primates

21 January 2018

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The specificity of TCR/pMHC interaction

21 January 2018

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Structural studies on the alphabeta T-cell receptor

21 January 2018

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Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes

21 January 2018

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Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis

21 January 2018

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HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

21 January 2018

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Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

21 January 2018

1 reference

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

21 January 2018

1 reference

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide

21 January 2018

1 reference

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains

21 January 2018

1 reference

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP

21 January 2018

1 reference

Natural killer cell receptors for major histocompatibility complex class I and related molecules in cytomegalovirus infection.

21 January 2018

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Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.

21 January 2018

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Cutting edge: the human cytomegalovirus UL40 gene product contains a ligand for HLA-E and prevents NK cell-mediated lysis

21 January 2018

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The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition

21 January 2018

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Identification of a human HLA-E-restricted CD8+ T cell subset in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine

21 January 2018

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HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells

21 January 2018

1 reference

HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes

21 January 2018

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Ligand recognition by alpha beta T cell receptors

21 January 2018

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Molecular interactions mediating T cell antigen recognition

21 January 2018

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Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

21 January 2018

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Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E

21 January 2018

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HLA-E allelic variants. Correlating differential expression, peptide affinities, crystal structures, and thermal stabilities

21 January 2018

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A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

21 January 2018

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HLA-E-restricted recognition of human cytomegalovirus by a subset of cytolytic T lymphocytes

21 January 2018

1 reference

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

21 January 2018

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Receptors for HLA class-I molecules in human natural killer cells.

21 January 2018

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KIR: diverse, rapidly evolving receptors of innate and adaptive immunity

21 January 2018

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Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations

21 January 2018

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The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues

21 January 2018

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Analysis of HLA-E peptide-binding specificity and contact residues in bound peptide required for recognition by CD94/NKG2.

21 January 2018

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Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells

21 January 2018

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The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

21 January 2018

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Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors

21 January 2018

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T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

21 January 2018

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Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

21 January 2018

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Differential effects of US2, US6 and US11 human cytomegalovirus proteins on HLA class Ia and HLA-E expression: impact on target susceptibility to NK cell subsets

21 January 2018

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Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region

21 January 2018

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

21 January 2018

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The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

21 January 2018

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Peptide-MHC class I tetrameric complexes display exquisite ligand specificity.

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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A graphical user interface to the CCP4 program suite

21 January 2018

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Synergistic effect of IFN-gamma and human cytomegalovirus protein UL40 in the HLA-E-dependent protection from NK cell-mediated cytotoxicity

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

TCR binding to peptide-MHC stabilizes a flexible recognition interface

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inferred from DOI database lookup

7 January 2021

based on heuristic

Interactions between NKG2x immunoreceptors and HLA-E ligands display overlapping affinities and thermodynamics

1 reference