Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma (Q28943313)

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14 March 2017

Daoud M. Meerzaman

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Myung-Soo Lyu

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Ying Hu

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Constance M. Cultraro

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Richard P. Finney

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Jenny M. Kelley

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Sharon I. Greenblum

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Cu V. Nguyen

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William L. Rowe

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Sweta Sharma

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Gang Wu

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Chunhua Yan

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Hongen Zhang

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Young-Hwa Chung

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Jeong A. Kim

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Neung Hwa Park

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Kenneth H. Buetow

Cancer burden in the year 2000. The global picture

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language of work or name

English

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publication date

1 December 2010

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14 March 2017

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2034–2043

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Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1

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A case-control study on family history of liver cancer as a risk factor for hepatocellular carcinoma in North Italy. Brescia HCC Study

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Localization of a susceptibility locus for hepatocellular carcinoma to chromosome 4q in a hepatitis B hyperendemic area

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-509C>T polymorphism in the TGF-beta1 gene promoter, impact on the hepatocellular carcinoma risk in Chinese patients with chronic hepatitis B virus infection

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Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis

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Molecular mechanisms of hepatocellular carcinoma

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Circular binary segmentation for the analysis of array-based DNA copy number data

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PLINK: a tool set for whole-genome association and population-based linkage analyses

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Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium

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CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

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Centre d'etude du polymorphisme humain (CEPH): collaborative genetic mapping of the human genome

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A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

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Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein

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Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein

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Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway.

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Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

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Lap2alpha expression is controlled by E2F and deregulated in various human tumors.

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Microarray-based CGH of sporadic and syndrome-related pheochromocytomas using a 0.1-0.2 Mb bacterial artificial chromosome array spanning chromosome arm 1p

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Genomic alterations identified by array comparative genomic hybridization as prognostic markers in tamoxifen-treated estrogen receptor-positive breast cancer

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Detection by fluorescence in situ hybridization of microdeletions at 1p36 in lymphomas, unidentified on cytogenetic analysis

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Copy number increase of 1p36.33 and mitochondrial genome amplification in Epstein-Barr virus-transformed lymphoblastoid cell lines

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T-kininogen, a cystatin-like molecule, inhibits ERK-dependent lymphocyte proliferation

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How TCRs bind MHCs, peptides, and coreceptors

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Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants

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Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections

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Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

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Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells

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Cancer-related inflammation

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

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