Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases (Q29347521)

11 April 2017

3 references

25 April 2019

12 September 2019

12 October 2019

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases (English)

1 reference

protein localization to presynapse

11 April 2017

3 references

25 April 2019

12 September 2019

12 October 2019

3 references

25 April 2019

12 September 2019

12 October 2019

1 reference

12 September 2019

1 reference

12 October 2019

1 reference

negative regulation of protein localization to presynapse

GO:1905383

1 reference

regulation of protein localization to presynapse

GO:1905385

1 reference

maintenance of synapse structure

GO:1905384

1 reference

positive regulation of protein localization to presynapse

GO:0099558

1 reference

2 references

GO:0099054

Dickkopf WNT signaling pathway inhibitor 1

1 reference

Wnt family member 7A

1 reference

Wnt family member 3A

1 reference

Wnt family member 5A

1 reference

Frizzled class receptor 1

1 reference

Dickkopf WNT signaling pathway inhibitor 3

1 reference

Dishevelled segment polarity protein 1

1 reference

Frizzled class receptor 5

1 reference

Patricia C Salinas

3

0 references

author name string

Silvia A Purro

series ordinal

1

1 reference

11 April 2017

Soledad Galli

series ordinal

2

1 reference

11 April 2017

language of work or name

1 reference

20 January 2014

1 reference

Journal of Molecular Cell Biology

11 April 2017

1 February 2014

3 references

25 April 2019

12 September 2019

12 October 2019

4 references

11 April 2017

25 April 2019

12 September 2019

12 October 2019

6

1 reference

11 April 2017

issue

1

1 reference

11 April 2017

page(s)

75-80

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Creative Commons Attribution 3.0 Unported

11 April 2017

copyright license

3 references

25 April 2019

12 September 2019

on focus list of Wikimedia project

12 October 2019

copyright status

copyrighted

0 references

ScienceSource

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cites work

Wnt/β-catenin signaling and disease

1 reference

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Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function

11 April 2017

1 reference

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Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca²⁺/Calmodulin-dependent protein kinase II

11 April 2017

1 reference

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Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

11 April 2017

1 reference

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Guidance molecules in synapse formation and plasticity

11 April 2017

1 reference

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Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli

11 April 2017

1 reference

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Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

A beta oligomers - a decade of discovery

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling

11 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

12 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt signaling: role in Alzheimer disease and schizophrenia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt signaling in neuromuscular junction development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt-5a is a synaptogenic factor with neuroprotective properties against Aβ toxicity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Soluble Aβ oligomer production and toxicity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

β-Adducin is required for stable assembly of new synapses and improved memory upon environmental enrichment

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt signaling during synaptic development and plasticity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Dysfunction and recovery of synapses in prion disease: implications for neurodegeneration.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Increased Dickkopf-1 expression in transgenic mouse models of neurodegenerative disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Nurturing brain plasticity: impact of environmental enrichment.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Emerging roles of Wnts in the adult nervous system

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Alzheimer's disease: synaptic dysfunction and Abeta

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Function and biological roles of the Dickkopf family of Wnt modulators

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Spatial training in a complex environment and isolation alter the spine distribution differently in rat CA1 pyramidal cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

Wnt-5a modulates recycling of functional GABAA receptors on hippocampal neurons.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT049

The secreted Wnt antagonist Dickkopf-1 is required for amyloid β-mediated synaptic loss.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FJMCB%2FMJT049

Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344549

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24449494

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JMCB/MJT049

1 reference

release_nzbbnv2oyjh3dhc6rcrfq6mvfa

11 April 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nzbbnv2oyjh3dhc6rcrfq6mvfa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4344549

0 references

1 reference