Genomewide association study for onset age in Parkinson disease (Q29417034)

21 June 2017

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Genomewide association study for onset age in Parkinson disease (English)

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21 June 2017

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13

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Nathan Pankratz

2

Nathan Pankratz

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Alexandra Dumitriu

Alexandra Dumitriu

3

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Jeanne C Latourelle

Jeanne C Latourelle

1

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Anita L DeStefano

Anita L DeStefano

8

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Stefano Goldwurm

Stefano Goldwurm

5

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Richard H Myers

Richard H Myers

12

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Gianni Pezzoli

6

Gianni Pezzoli

1 reference

21 June 2017

10

James F Gusella

1 reference

ORCID Public Data File 2021

21 June 2017

1 reference

Michael W Nagle

1 reference

ORCID Public Data File 2021

Cheryl A. Halter

9

Cheryl Halter

1 reference

21 June 2017

4

Jemma B Wilk

1 reference

21 June 2017

Claudio B Mariani

7

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21 June 2017

William C Nichols

11

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21 June 2017

PROGENI Investigators, Coordinators and Molecular Genetic Laboratories

14

1 reference

21 June 2017

GenePD Investigators, Coordinators and Molecular Genetic Laboratories

15

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21 June 2017

language of work or name

English

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publication date

22 September 2009

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21 June 2017

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21 June 2017

10

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21 June 2017

98

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Creative Commons Attribution 2.0 Generic

21 June 2017

1

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copyright license

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copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1186/1471-2350-10-98

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cites work

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

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Estimation of significance thresholds for genomewide association scans

18 April 2017

1 reference

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Genetic determinants of hair, eye and skin pigmentation in Europeans

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

PLINK: a tool set for whole-genome association and population-based linkage analyses

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

A novel AAK1 splice variant functions at multiple steps of the endocytic pathway

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

18 April 2017

Whole-genome genotyping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

High-resolution whole-genome association study of Parkinson disease.

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

The International HapMap Project

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Mutations of the P gene in oculocutaneous albinism, ocular albinism, and Prader-Willi syndrome plus albinism

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

A new multipoint method for genome-wide association studies by imputation of genotypes

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

The future of genetic studies of complex human diseases

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Alpha-synuclein and familial Parkinson's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Genomewide association study for susceptibility genes contributing to familial Parkinson disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Common variants in the GDF5-UQCC region are associated with variation in human height

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Replication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Endoplasmic reticulum stress signaling in disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Complex segregation analysis of Parkinson's disease: The Mayo Clinic Family Study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

ER stress and neurodegenerative diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Atypical cancer pattern in patients with Parkinson's disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Misfolded proteins, endoplasmic reticulum stress and neurodegeneration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Epidemiology of neurodegeneration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

P gene as an inherited biomarker of human eye color.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Segregation analysis of Parkinson disease revealing evidence for a major causative gene.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Age at onset in two common neurodegenerative diseases is genetically controlled

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Human pigmentation genes: identification, structure and consequences of polymorphic variation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Young-onset Parkinson's disease revisited--clinical features, natural history, and mortality

3 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Segregation analysis of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

HFE gene mutations in a population of Italian Parkinson's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

A Prospective Cohort Study of Cancer Incidence Following the Diagnosis of Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Pigmentation genes link Parkinson's disease to melanoma, opening a window on both etiologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Activation of the unfolded protein response in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Genes influencing Parkinson disease onset: replication of PARK3 and identification of novel loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Mutations in LRRK2 other than G2019S are rare in a north american–based sample of familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Absence of previously reported variants in theSCNA (G88C and G209A),NR4A2 (T291D and T245G) and theDJ-1 (T497C) genes in familial Parkinson's disease from theGenePD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Evidence of Linkage and Association with Body Fatness and Abdominal Fat on Chromosome 15q26*

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Malignant Melanoma and Other Types of Cancer Preceding Parkinson Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-98

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758866

Reliability of reported age at onset for Parkinson's disease

26 November 2018

1 reference

12 December 2020

Genetics of Parkinson's disease

1 reference

12 December 2020

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease

1 reference

12 December 2020

Evaluation of LRRK2 G2019S penetrance: Relevance for genetic counseling in Parkinson disease

1 reference

12 December 2020

Genetic model testing and statistical power in population-based association studies of quantitative traits

1 reference

12 December 2020

Multilocus OCA2 genotypes specify human iris colors

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2350-10-98

1 reference

Dimensions Publication ID

21 June 2017

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0 references

1 reference