A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis (Q29417136)

16 April 2017

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A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis (English)

1 reference

genome-wide association study

16 April 2017

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amyotrophic lateral sclerosis

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author

Adriano Chiò

37

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Wim Robberecht

36

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Philip Van Damme

35

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Michael Sendtner

39

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Francesco Saccà

Francesco Saccà

21

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Barbara Castellotti

Barbara Castellotti

13

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Paolo Bongioanni

Paolo Bongioanni

22

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Aleksey Shatunov

Aleksey Shatunov

30

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Francesca Luisa Conforti

Francesca L Conforti

18

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Nicola Ticozzi

Nicola Ticozzi

56

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Silvana Penco

Silvana Penco

23

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Massimiliano Filosto

Massimiliano Filosto

26

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Michael E. Weale

Michael E Weale

51

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Stefania Corti

Stefania Corti

10

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Cristina Cereda

Cristina Cereda

9

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Maurizio Inghilleri

Maurizio Inghilleri

20

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Cinzia Gellera

Cinzia Gellera

3

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Vincenzo Silani

Vincenzo Silani

65

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Mauro Ceroni

Mauro Ceroni

57

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Pamela Shaw

Pamela J Shaw

32

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Sandro Sorbi

Sandro Sorbi

25

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Giacomo P Comi

Giacomo P Comi

59

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Orla Hardiman

Orla Hardiman

42

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Gabriele Siciliano

Gabriele Siciliano

19

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Cathryn Lewis

Cathryn M Lewis

52

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Isabella Fogh

Isabella Fogh

1

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Christopher Shaw

Christopher E Shaw

50

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Karen E Morrison

Karen E Morrison

33

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Ammar Al-Chalabi

63

Ammar Al-Chalabi

1 reference

16 April 2017

41

Vincent Meininger

1 reference

16 April 2017

Leonard H van den Berg

61

Leonard H van den Berg

1 reference

16 April 2017

14

Letizia Mazzini

1 reference

16 April 2017

48

Jan H Veldink

1 reference

16 April 2017

43

Peter M Andersen

1 reference

16 April 2017

7

Lucia Corrado

1 reference

16 April 2017

38

Bryan J Traynor

1 reference

16 April 2017

Valentina Escott-Price

6

Valentina Moskvina

1 reference

16 April 2017

31

Ashley Jones

1 reference

16 April 2017

45

Jonathan D Glass

1 reference

16 April 2017

55

John E Landers

1 reference

16 April 2017

2

Antonia Ratti

1 reference

16 April 2017

5

Cinzia Tiloca

1 reference

16 April 2017

12

Daniela Calini

1 reference

16 April 2017

16

Stella Gagliardi

1 reference

16 April 2017

40

Judith Melki

1 reference

16 April 2017

47

Frank P Diekstra

1 reference

16 April 2017

54

Robert H Brown

1 reference

16 April 2017

Kuang Lin

4

1 reference

16 April 2017

Gianni Sorarù

8

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16 April 2017

Davide Gentilini

11

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16 April 2017

Giorgia Querin

15

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16 April 2017

Roberto Del Bo

17

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16 April 2017

Massimo Corbo

24

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16 April 2017

Alessandra Ferlini

27

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16 April 2017

Anna M Di Blasio

28

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16 April 2017

Stefano Signorini

29

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16 April 2017

Anne E Farmer

34

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16 April 2017

Nigel P Leigh

44

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16 April 2017

Daniel Overste

46

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16 April 2017

Michael A van Es

49

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16 April 2017

Julie Williams

53

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16 April 2017

Elena Pegoraro

58

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16 April 2017

Sandra D'Alfonso

60

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16 April 2017

Franco Taroni

62

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16 April 2017

John Powell

64

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16 April 2017

SLAGEN Consortium and Collaborators

66

1 reference

16 April 2017

20 November 2013

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16 April 2017

Human Molecular Genetics

1 reference

16 April 2017

23

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16 April 2017

2220-2231

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16 April 2017

8

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Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

16 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genome-wide association study reveals genetic risk underlying Parkinson's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

PLINK: a tool set for whole-genome association and population-based linkage analyses

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Whole-genome analysis of sporadic amyotrophic lateral sclerosis

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Population structure and eigenanalysis

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Principal components analysis corrects for stratification in genome-wide association studies

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Measuring inconsistency in meta-analyses

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

GCTA: a tool for genome-wide complex trait analysis

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

METAL: fast and efficient meta-analysis of genomewide association scans

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

A new multipoint method for genome-wide association studies by imputation of genotypes

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genotype imputation for genome-wide association studies

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits

18 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

C9ORF72 repeat expansion in a large Italian ALS cohort: evidence of a founder effect

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

An estimate of amyotrophic lateral sclerosis heritability using twin data.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Wallerian degeneration, wld(s), and nmnat

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Heterogeneity in meta-analyses of genome-wide association investigations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Amyotrophic lateral sclerosis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

The epidemiology of ALS and the role of population-based registries

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

An evidence-based medicine approach to the evaluation of the role of exogenous risk factors in sporadic amyotrophic lateral sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Consensus guidelines for the design and implementation of clinical trials in ALS. World Federation of Neurology committee on Research

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

The sex ratio in amyotrophic lateral sclerosis: A population based study.

3 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

A genome-wide association study of sporadic ALS in a homogenous Irish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

Including known covariates can reduce power to detect genetic effects in case-control studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

Analysis of C9orf72 repeat expansion in 563 Japanese patients with amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT587

ALSoD: A user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Association between DPP6 polymorphism and the risk of sporadic amyotrophic lateral sclerosis in Chinese patients

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3959809

Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians

26 November 2018

1 reference

12 December 2020

No association of DPP6 with amyotrophic lateral sclerosis in an Italian population

1 reference

12 December 2020

Neuroscience. dSarm-ing axon degeneration

1 reference

12 December 2020

The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDT587

1 reference

2744475

2744475

1 reference

1 reference

1 reference