The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans (Q29619760)

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scientific article (publication date: 6 August 2002)

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English	The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans	scientific article (publication date: 6 August 2002)

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scholarly article

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The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Caenorhabditis elegans

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protein aggregation

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based on heuristic

inferred from title

author name string

Morley JF

1

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30 April 2017

Brignull HR

2

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30 April 2017

Weyers JJ

3

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Morimoto RI

4

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30 April 2017

language of work or name

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30 April 2017

publication date

6 August 2002

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30 April 2017

Proceedings of the National Academy of Sciences of the United States of America

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30 April 2017

99

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16

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30 April 2017

10417-22

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

1 reference

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A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions

1 reference

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Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human

1 reference

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Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

1 reference

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1 reference

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A Drosophila model of Parkinson's disease

1 reference

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

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A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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30 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.152161099

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Aging and resistance to oxidative damage in Caenorhabditis elegans

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The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

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Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

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30 April 2017

The genetics of Caenorhabditis elegans

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30 April 2017

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

1 reference

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3 June 2018

A conserved regulatory system for aging

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3 June 2018

Beyond the Qs in the polyglutamine diseases

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3 June 2018

Diverse Caenorhabditis elegans genes that are upregulated in dauer larvae also show elevated transcript levels in long-lived, aged, or starved adults

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3 June 2018

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

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3 June 2018

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

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Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

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3 June 2018

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

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Glutamine repeats and neurodegenerative diseases: molecular aspects

1 reference

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Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.

1 reference

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3 June 2018

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

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3 June 2018

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

1 reference

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3 June 2018

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

1 reference

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3 June 2018

Deadly conformations--protein misfolding in prion disease

1 reference

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3 June 2018

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size

1 reference

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Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

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Trinucleotide repeat length instability and age of onset in Huntington's disease

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Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

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Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.

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12 December 2020

based on heuristic

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Effects of neurohormonal stress and aging on the activation of mammalian heat shock factor 1

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https://pubmed.ncbi.nlm.nih.gov/12122205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.152161099

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2002PNAS...9910417M

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12122205

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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