The immune contexture in human tumours: impact on clinical outcome (Q29620667)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

30 April 2017

4

Galon J

1 reference

30 April 2017

Fridman WH

1

1 reference

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30 April 2017

Pagès F

series ordinal

2

1 reference

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30 April 2017

Sautès-Fridman C

series ordinal

3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

15 March 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

30 April 2017

published in

Nature Reviews Cancer

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volume

12

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page(s)

298-306

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issue

4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

The three Es of cancer immunoediting

30 April 2017

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Adaptive immunity maintains occult cancer in an equilibrium state

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

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IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

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Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

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The adaptive immunologic microenvironment in colorectal cancer: a novel perspective

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Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer

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Cancer-related inflammation

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Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures

31 March 2020

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Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy

31 March 2020

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

31 March 2020

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Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

31 March 2020

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Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

31 March 2020

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Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients

31 March 2020

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Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.

31 March 2020

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Tumor-infiltrating cytotoxic T cells but not regulatory T cells predict outcome in anal squamous cell carcinoma

31 March 2020

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Incidence and prognostic impact of FoxP3+ regulatory T cells in human gliomas.

31 March 2020

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Leukocyte infiltration and tumor cell plasticity are parameters of aggressiveness in primary cutaneous melanoma.

31 March 2020

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Prognostic significance and mechanism of Treg infiltration in human brain tumors.

31 March 2020

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FOXP3+ cell density in primary tumor has no prognostic impact in patients with cutaneous malignant melanoma

31 March 2020

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An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer

31 March 2020

1 reference

Localisation pattern of Foxp3+ regulatory T cells is associated with clinical behaviour in gastric cancer

31 March 2020

1 reference

Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma

31 March 2020

1 reference

Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways.

31 March 2020

1 reference

Prognostic Value of Tumor-Infiltrating CD4+ T-Cell Subpopulations in Head and Neck Cancers

31 March 2020

1 reference

High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma.

31 March 2020

1 reference

Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer.

31 March 2020

1 reference

High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

31 March 2020

1 reference

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

31 March 2020

1 reference

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

31 March 2020

1 reference

Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma

31 March 2020

1 reference

FOXP3 and survival in urinary bladder cancer.

31 March 2020

1 reference

Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism.

31 March 2020

1 reference

Th17 cells in cancer: help or hindrance?

31 March 2020

1 reference

Higher levels of GATA3 predict better survival in women with breast cancer

31 March 2020

1 reference

Prognostic impact of tumour-infiltrating Th2 and regulatory T cells in classical Hodgkin lymphoma

31 March 2020

1 reference

The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma

31 March 2020

1 reference

Prognostic value of intratumoral natural killer cells in gastric carcinoma

31 March 2020

1 reference

Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer.

31 March 2020

1 reference

Impact of immune parameters on long-term survival in metastatic renal cell carcinoma

31 March 2020

1 reference

Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma

31 March 2020

1 reference

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

31 March 2020

1 reference

Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions.

31 March 2020

1 reference

Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells

31 March 2020

1 reference

Differing phenotypes between intraepithelial and stromal lymphocytes in early-stage tongue cancer

31 March 2020

1 reference

Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes

31 March 2020

1 reference

Macrophage polarization to a unique phenotype driven by B cells.

31 March 2020

1 reference

FcRgamma activation regulates inflammation-associated squamous carcinogenesis.

31 March 2020

1 reference

B cells and macrophages in cancer: yin and yang.

31 March 2020

1 reference

Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells

31 March 2020

1 reference

Naturally occurring B-cell responses to breast cancer

31 March 2020

1 reference

Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors

31 March 2020

1 reference

B cells are required for optimal CD4+ and CD8+ T cell tumor immunity: therapeutic B cell depletion enhances B16 melanoma growth in mice

31 March 2020

1 reference

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

31 March 2020

1 reference

Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes

31 March 2020

1 reference

Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer.

31 March 2020

1 reference

Gene-expression signatures in breast cancer

31 March 2020

1 reference

Implication of tumor microenvironment in the resistance to chemotherapy in breast cancer patients

31 March 2020

1 reference

Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

31 March 2020

1 reference

Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy

31 March 2020

1 reference

Favorable prognosis of renal cell carcinoma with increased expression of chemokines associated with a Th1-type immune response

31 March 2020

1 reference

Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma

31 March 2020

1 reference

Strong expression of the lymphoattractant C-X-C chemokine Mig is associated with heavy infiltration of T cells in human malignant melanoma

31 March 2020

1 reference

Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer.

31 March 2020

1 reference

Characterization of chemokines and adhesion molecules associated with T cell presence in tertiary lymphoid structures in human lung cancer.

31 March 2020

1 reference

Tumor immunosurveillance in human cancers

31 March 2020

1 reference

Tumor microenvironment is multifaceted

31 March 2020

1 reference

Coordination of intratumoral immune reaction and human colorectal cancer recurrence.

31 March 2020

1 reference

A decrease of regulatory T cells correlates with overall survival after sunitinib-based antiangiogenic therapy in metastatic renal cancer patients

31 March 2020

1 reference

Systems biology and new technologies enable predictive and preventative medicine.

31 March 2020

1 reference

TNM staging in colorectal cancer: T is for T cell and M is for memory.

31 March 2020

1 reference

Cancer immunology--analysis of host and tumor factors for personalized medicine

31 March 2020

1 reference

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

31 March 2020

1 reference

PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine

31 March 2020

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Effective cancer therapy through immunomodulation

31 March 2020

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Dacarbazine Promotes Stromal Remodeling and Lymphocyte Infiltration in Cutaneous Melanoma Lesions

31 March 2020

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Immunological aspects of cancer chemotherapy

31 March 2020

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Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients

31 March 2020

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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

31 March 2020

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Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.

31 March 2020

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Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy

31 March 2020

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31 March 2020

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Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

31 March 2020

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Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

31 March 2020

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Randomized trial of autologous cellular immunotherapy with sipuleucel-T in androgen-dependent prostate cancer

31 March 2020

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Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer

31 March 2020

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Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response

31 March 2020

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Trial Watch: Monoclonal antibodies in cancer therapy

31 March 2020

1 reference

The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity

31 March 2020

1 reference

Model predicting survival in stage I melanoma based on tumor progression

31 March 2020

1 reference

Immunocytochemical Analysis of the Cellular Infiltrate in Primary Regressing and Non-Regressing Malignant Melanoma

31 March 2020

1 reference

High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates

31 March 2020

1 reference

Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

31 March 2020

1 reference

Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma

31 March 2020

1 reference

Tumor cell expression of HLA-DM associates with a Th1 profile and predicts improved survival in breast carcinoma patients.

31 March 2020

1 reference

Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

31 March 2020

1 reference

In situ cytokine production by breast cancer tumor-infiltrating lymphocytes

31 March 2020

1 reference

Clinical significance of immune cell infiltration within gallbladder cancer

31 March 2020

1 reference

CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma

31 March 2020

1 reference

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

31 March 2020

1 reference

Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

31 March 2020

1 reference

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

31 March 2020

1 reference

Interferon-gamma expression is an independent prognostic factor in ovarian cancer.

31 March 2020

1 reference

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

31 March 2020

1 reference

Lymphocyte subsets and T(h)1/T(h)2 immune responses in patients with adenocarcinoma of the oesophagus or oesophagogastric junction: relation to pTNM stage and clinical outcome

31 March 2020

1 reference

The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma

31 March 2020

1 reference

Analysis of the T cell receptor variability of tumor-infiltrating lymphocytes in colorectal carcinomas

31 March 2020

1 reference

Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: A potential role for dysregulation of the transforming growth factor-β pathway

31 March 2020

1 reference

Immunology and immunotherapy of colorectal cancer

31 March 2020

1 reference

Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells

31 March 2020

1 reference

From Dukes through Jass: pathological prognostic indicators in rectal cancer

31 March 2020

1 reference

Lymphocytic infiltration and survival in rectal cancer

31 March 2020

1 reference

Clinical impact of tumor-infiltrating lymphocytes for survival in stage II colon cancer

31 March 2020

1 reference

CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer.

31 March 2020

1 reference

Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis

31 March 2020

1 reference

Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review

31 March 2020

1 reference

Effector memory T cells, early metastasis, and survival in colorectal cancer

31 March 2020

1 reference

Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability

31 March 2020

1 reference

Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer

31 March 2020

1 reference

Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor

31 March 2020

1 reference

Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical study

31 March 2020

1 reference

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype

31 March 2020

1 reference

IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma.

31 March 2020

1 reference

Increased intratumoral FOXP3-positive regulatory immune cells during interleukin-2 treatment in metastatic renal cell carcinoma

31 March 2020

1 reference

The prognostic impact of M-CSF, CSF-1 receptor, CD68 and CD3 in prostatic carcinoma

31 March 2020

1 reference

Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma

31 March 2020

1 reference

Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer

31 March 2020

1 reference

Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.

31 March 2020

1 reference

Predominant infiltration of macrophages and CD8(+) T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer.

31 March 2020

1 reference

CD4+ T cells in cancer stroma, not CD8+ T cells in cancer cell nests, are associated with favorable prognosis in human non-small cell lung cancers

31 March 2020

1 reference

Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients

31 March 2020

1 reference

Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients

31 March 2020

1 reference

Tumor-infiltrating Foxp3+ regulatory T cells are correlated with cyclooxygenase-2 expression and are associated with recurrence in resected non-small cell lung cancer

31 March 2020

1 reference

Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells

31 March 2020

1 reference

CD8+ tumor-infiltrating lymphocytes together with CD4+ tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma

31 March 2020

1 reference

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

31 March 2020

1 reference

Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients

31 March 2020

1 reference

IFN-gamma produced by human papilloma virus-18 E6-specific CD4+ T cells predicts the clinical outcome after surgery in patients with high-grade cervical lesions

31 March 2020

1 reference

Dendritic cell infiltration and prognosis of human hepatocellular carcinoma.

31 March 2020

1 reference

Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration.

31 March 2020

1 reference

Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma

31 March 2020

1 reference

Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients.

31 March 2020

1 reference

Evaluations of interferon-γ/interleukin-4 ratio and neutrophil/lymphocyte ratio as prognostic indicators in gastric cancer patients

31 March 2020

1 reference

Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients

31 March 2020

1 reference

TH1 predominance is associated with improved survival in pediatric medulloblastoma patients

31 March 2020

1 reference

Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

31 March 2020

1 reference

Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.

31 March 2020

1 reference

12 December 2020

CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer

1 reference

12 December 2020

Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma

1 reference

12 December 2020

The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy

1 reference

12 December 2020

Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function

1 reference

12 December 2020

Evidence for an antigen-driven humoral immune response in medullary ductal breast cancer.

1 reference

12 December 2020

The number of intratumoral dendritic cells and zeta-chain expression in T cells as prognostic and survival biomarkers in patients with oral carcinoma.

1 reference

12 December 2020

CD40 ligand-CD40 interaction induces chemokines in cervical carcinoma cells in synergism with IFN-gamma.

1 reference

12 December 2020

Crohn's-like lymphoid reaction and colorectal carcinoma: a potential histologic prognosticator

1 reference

12 December 2020

Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity

1 reference

12 December 2020

Tumour-infiltrating lymphocytes: A prognostic factor of PSA-free survival in patients with local prostate carcinoma treated by radical prostatectomy

1 reference

12 December 2020

High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients

1 reference

12 December 2020

Increased mRNA expression of chemokines in hepatocellular carcinoma with tumor-infiltrating lymphocytes

1 reference

12 December 2020

CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma

1 reference

12 December 2020

Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma

1 reference

12 December 2020

Prognostic significance of T helper 1 and 2 and T cytotoxic 1 and 2 cells in patients with non-small cell lung cancer

1 reference

12 December 2020

Clinical significance of poor CD3 response in head and neck cancer.

1 reference

12 December 2020

Peri- and intratumoral T and B lymphocytic infiltration in breast cancer

1 reference

12 December 2020

Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer.

1 reference

12 December 2020

[Prognostic significance of natural killer cell infiltration in hepatocellular carcinoma]

1 reference

12 December 2020

Relative expression levels of Th1 and Th2 cytokine mRNA are independent prognostic factors in patients with ovarian cancer.

1 reference

12 December 2020

Evidence for in situ amplification of cytotoxic T-lymphocytes with antitumor activity in a human regressive melanoma.

1 reference

12 December 2020

Utility of tumour-infiltrating CD25+FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanoma

1 reference

12 December 2020

Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas.

1 reference

12 December 2020

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

272007

1034518617

0 references

272007

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22419253

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017