Protein unc-112 CELE_C47E8.7 (Q29798409)

FERM superfamily, second domain

1 reference

Kindlin/fermitin

1 reference

pleckstrin homology domain, protein family

1 reference

Kindlin/fermitin, PH domain, protein family

1 reference

Band 4.1 domain, protein family

1 reference

FERM central domain, protein family

1 reference

FERM conserved site, protein family

1 reference

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

structural molecule activity

IPI

1 reference

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

5 references

1 January 2018

Suppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

IPI

protein self-association

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

cell adhesion molecule binding

IPI

1 reference

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

IEA

cell-substrate junction

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

striated muscle dense body

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

2 references

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

IDA

muscle organ development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 reference

1 January 2018

The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of smooth muscle contraction

1 reference

1 January 2018

pat-4/ILK and unc-112/Mig-2 are required for gonad function in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of ovulation

1 reference

1 January 2018

pat-4/ILK and unc-112/Mig-2 are required for gonad function in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

establishment of protein localization to organelle

1 reference

1 January 2018

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

regulation of engulfment of apoptotic cell

1 reference

1 January 2018

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of distal tip cell migration

1 reference

1 January 2018

pat-4/ILK and unc-112/Mig-2 are required for gonad function in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of myosin II filament organization

1 reference

1 January 2018

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

integrin-mediated signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

mitochondrion organization

IEA

1 reference

1 January 2018

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of locomotion

1 reference

1 January 2018

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

muscle cell cellular homeostasis

1 reference

1 January 2018

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

positive regulation of sarcomere organization

1 reference

1 January 2018

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q18685

1 reference

FERM central domain

1 reference

Band 4.1 domain

1 reference

pleckstrin homology domain

1 reference

Kindlin/fermitin, PH domain

1 reference