Serine/threonine-protein kinase unc-51 CELE_Y60A3A.1 (Q29806848)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23023

serine/threonine-protein kinase Unc-51

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23023

Serine/threonine-protein kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

protein serine/threonine kinase activity

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23023&geneProductId=UniProtKB:Q23023

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23023&geneProductId=UniProtKB:Q23023

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23023&geneProductId=UniProtKB:Q23023

16 July 2018

protein binding

4 references

1 January 2018

The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

protein serine/threonine kinase activity

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

cell component

axon

1 reference

1 January 2018

Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

neuron projection

soma

3 references

1 January 2018

The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 January 2018

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

phagophore assembly site

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

cytosol

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

membrane

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

biological process

autophagy

1 reference

1 January 2018

Autophagy genes are essential for dauer development and life-span extension in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

axonogenesis

1 reference

1 January 2018

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

axon guidance

1 reference

1 January 2018

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

determination of adult lifespan

1 reference

1 January 2018

Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

regulation of cell size

1 reference

1 January 2018

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

embryo development ending in birth or egg hatching

1 reference

1 January 2018

Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

programmed cell death

1 reference

1 January 2018

Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

cell migration

1 reference

1 January 2018

Mechanisms controlling sex myoblast migration in Caenorhabditis elegans hermaphrodites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

1 reference

1 January 2018

regulation of axon extension

1 reference

1 January 2018

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

regulation of protein localization

1 reference

1 January 2018

The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

regulation of multicellular organism growth

1 reference

1 January 2018

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

dauer larval development

1 reference

1 January 2018

Autophagy genes are essential for dauer development and life-span extension in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

apoptotic cell clearance

1 reference

1 January 2018

The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

nematode male tail tip morphogenesis

1 reference

1 January 2018

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

protein autophosphorylation

1 reference

16 July 2018

The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23023&geneProductId=UniProtKB:Q23023

autophagosome assembly

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023

regulation of autophagy

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23023