F-box/WD repeat-containing protein sel-10 CELE_F55B12.3 (Q29806964)

http://www.ebi.ac.uk/interpro/protein/Q93794

WD40-repeat-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q93794

F-box-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q93794

F-box protein

1 reference

WD40 repeat, protein family

1 reference

WD40 repeat, conserved site, protein family

1 reference

G-protein beta WD-40 repeat, protein family

1 reference

Notch signaling is antagonized by SAO-1, a novel GYF-domain protein that interacts with the E3 ubiquitin ligase SEL-10 in Caenorhabditis elegans

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

10 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

Protein interaction mapping in C. elegans using proteins involved in vulval development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

A map of the interactome network of the metazoan C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

Identification of potential interaction networks using sequence-based searches for conserved protein-protein interactions or "interologs".

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels

IPI

protein kinase binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

protein homodimerization activity

IPI

1 reference

1 January 2018

SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 January 2018

Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

multicellular organism development

IBA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

regulation of Notch signaling pathway

IEA

1 reference

1 January 2018

Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

negative regulation of centrosome duplication

IGI

1 reference

1 January 2018

The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

regulation of protein stability

IEA

1 reference

1 January 2018

The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

regulation of vulval development

IMP

1 reference

1 January 2018

SEL-10/Fbw7-dependent negative feedback regulation of LIN-45/Braf signaling in C. elegans via a conserved phosphodegron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

negative regulation of Notch signaling pathway

IMP

1 reference

1 January 2018

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

female sex differentiation

IGI

ribosomal large subunit assembly

IMP

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IBA

Notch signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q93794