Ret oncogene Dmel_CG14396 (Q29810462)

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

protein kinase activity

1 reference

8 April 2019

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells

IDA

receptor tyrosine kinase

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

transmembrane signaling receptor activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

transmembrane receptor protein tyrosine kinase activity

3 references

8 April 2019

A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

integral component of plasma membrane

ISS

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

integral component of membrane

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

integral component of plasma membrane

3 references

8 April 2019

Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

Drosophila RET contains an active tyrosine kinase and elicits neurotrophic activities in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

positive regulation of cell-matrix adhesion

biological process

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

Protein kinases and phosphatases in the Drosophila genome

IMP

protein phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

actin filament organization

IEA

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

peptidyl-tyrosine phosphorylation

IMP

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

negative regulation of signal transduction

IEA

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

negative regulation of apoptotic process

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

positive regulation of ERK1 and ERK2 cascade

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7KT06&geneProductId=UniProtKB:Q7KT06

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

nervous system development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

positive regulation of MAPK cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

positive regulation of protein kinase B signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

regulation of dendrite development

1 reference

8 April 2019

Ret and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory Neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7KT06

tyrosine-protein kinase, active site

IMP

has part(s)

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference