Tout-velu Dmel_CG10117 (Q29814757)

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Protein found in Drosophila melanogaster

tout-velo
CG10117 gene product from transcript CG10117-RB
lethal (2) SH0631
ttv-PB
ttv-PC
tout velour
ttv
tout-velu
toutvelu
CG10117-PD
CG10117-PC
ttv-PA
CG10117-PB
tout velu
CG10117-PA
ttv-PD

Language	Label	Description	Also known as
English	Tout-velu Dmel_CG10117	Protein found in Drosophila melanogaster	tout-velo CG10117 gene product from transcript CG10117-RB lethal (2) SH0631 ttv-PB ttv-PC tout velour ttv tout-velu toutvelu CG10117-PD CG10117-PC ttv-PA CG10117-PB tout velu CG10117-PA ttv-PD

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9V730

nucleotide-diphospho-sugar transferases

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9V730

Exostosin , C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

3 references

9 May 2019

Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Heparan sulfate polymerization in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

glucuronosyltransferase activity

determination method

1 reference

10 September 2018

Glycosylation of proteins in plants and invertebrates.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

transferase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

metal ion binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

determination method

acetylglucosaminyltransferase activity

determination method

1 reference

9 May 2019

Heparan sulfate polymerization in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

glucuronosyltransferase activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

endoplasmic reticulum

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

endoplasmic reticulum membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

Golgi apparatus

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

integral component of membrane

determination method

3 references

9 May 2019

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

determination method

1 reference

31 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

biological process

glycosaminoglycan biosynthetic process

determination method

3 references

9 May 2019

Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

N-acetylglucosamine metabolic process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

multicellular organism development

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

determination method

1 reference

9 May 2019

Reception of Slit requires only the chondroitin-sulphate-modified extracellular domain of Syndecan at the target cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

regulation of smoothened signaling pathway

determination method

heparan sulfate proteoglycan biosynthetic process

determination method

10 references

10 September 2018

Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Cholesterol modification of proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Glycosylation of proteins in plants and invertebrates.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Heparan sulfate polymerization in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

10 September 2018

Heparan sulfate polymerization in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

determination method

Wnt signaling pathway

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

positive regulation of smoothened signaling pathway

determination method

intracellular distribution of mitochondria

determination method

1 reference

31 January 2018

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

synaptic vesicle endocytosis

determination method

1 reference

31 January 2018

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

synapse organization

determination method

1 reference

31 January 2018

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730

determination method

positive regulation of canonical Wnt signaling pathway

determination method

heparan sulfate proteoglycan biosynthetic process

determination method

8 references

9 May 2019

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Heparan sulfate polymerization in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

9 May 2019

Heparan sulfate polymerization in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

determination method

1 reference

9 May 2019

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730

determination method

Exostosin , C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9V730

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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