Rac2 Dmel_CG8556 (Q29815788)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48554

small GTPase Rho

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P48554

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

1 reference

8 April 2019

GTPase activity

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila

3 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

31 January 2018

crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

31 January 2018

protein binding

3 references

8 April 2019

The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

Slit Stimulation Recruits Dock and Pak to the Roundabout Receptor and Increases Rac Activity to Regulate Axon Repulsion at the CNS Midline

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

protein kinase binding

1 reference

10 September 2018

Phylogenetic and structural analysis of the Drosophila melanogaster p21-activated kinase DmPAK3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

GTPase activity

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

GTP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

intracellular anatomical structure

cell component

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

1 reference

10 September 2018

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

1 reference

10 September 2018

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

1 reference

8 April 2019

cytoplasm

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

cytoplasmic vesicle

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

cell projection

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

biological process

cell morphogenesis

1 reference

8 April 2019

A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

morphogenesis of an epithelium

1 reference

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

aggressive behavior

1 reference

8 April 2019

The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis

IDA

1 reference

8 April 2019

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

IDA

phagocytosis

Rac2 is a major actor of Drosophila resistance to Pseudomonas aeruginosa acting in phagocytic cells

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

JNK cascade

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

small GTPase mediated signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

1 reference

8 April 2019

Rho protein signal transduction

1 reference

31 January 2018

The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48554&geneProductId=UniProtKB:P48554

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

1 reference

8 April 2019

germ-band shortening

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

dorsal closure

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

8 April 2019

crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

dorsal closure, elongation of leading edge cells

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

open tracheal system development

1 reference

8 April 2019

Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

tracheal outgrowth, open tracheal system

1 reference

8 April 2019

Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

salivary gland morphogenesis

1 reference

8 April 2019

Rac function in epithelial tube morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

myoblast fusion

1 reference

8 April 2019

Myoblast fusion in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

mating behavior

1 reference

8 April 2019

The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

feeding behavior

1 reference

8 April 2019

The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

head involution

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

regulation of lipid storage

1 reference

8 April 2019

The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

muscle attachment

1 reference

8 April 2019

Drosophila importin-7 functions upstream of the Elmo signaling module to mediate the formation and stability of muscle attachments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

lamellipodium assembly

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

actin cytoskeleton reorganization

1 reference

8 April 2019

Coordination of Rho family GTPase activities to orchestrate cytoskeleton responses during cell wound repair.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

adherens junction maintenance

1 reference

8 April 2019

Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

melanotic encapsulation of foreign target

1 reference

8 April 2019

A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

defense response to bacterium

1 reference

8 April 2019

Rac2 is a major actor of Drosophila resistance to Pseudomonas aeruginosa acting in phagocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

dorsal appendage formation

1 reference

8 April 2019

Following the 'tracks': Tramtrack69 regulates epithelial tube expansion in the Drosophila ovary through Paxillin, Dynamin, and the homeobox protein Mirror

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

regulation of axonogenesis

1 reference

8 April 2019

Rho GTPases regulate axon growth through convergent and divergent signaling pathways.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

actin filament bundle assembly

1 reference

8 April 2019

The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

positive regulation of wound healing

1 reference

8 April 2019

Coordination of Rho family GTPase activities to orchestrate cytoskeleton responses during cell wound repair.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

mesodermal cell migration

1 reference

8 April 2019

FGF signalling and the mechanism of mesoderm spreading in Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

motor neuron axon guidance

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

cell migration

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

actin cytoskeleton organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48554

small GTP-binding protein domain

has part(s)

1 reference

InterPro Release 71.0