Abl tyrosine kinase Dmel_CG4032 (Q29817786)

Protein kinase-like domain superfamily

1 reference

SH3-like domain superfamily

1 reference

SH2 domain superfamily

1 reference

F-actin binding domain, protein family

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

Tyrosine-protein kinase ABL, SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

protein kinase activity

1 reference

8 April 2019

protein tyrosine kinase activity

10 references

1 January 2018

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 January 2018

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

non-membrane spanning protein tyrosine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

4 references

8 April 2019

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

protein tyrosine kinase activity

9 references

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions

TAS

muscle tendon junction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

extrinsic component of plasma membrane

1 reference

8 April 2019

Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

The Hem protein mediates neuronal migration by inhibiting WAVE degradation and functions opposite of Abelson tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

morphogenesis of an epithelium

1 reference

1 January 2018

Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

epithelial cell morphogenesis

NAS

1 reference

8 April 2019

Abelson kinase regulates epithelial morphogenesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

chemical synaptic transmission

1 reference

8 April 2019

latheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

cytoplasmic transport, nurse cell to oocyte

1 reference

8 April 2019

Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila

ventral furrow formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

7 references

8 April 2019

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

central nervous system development

IGI

1 reference

8 April 2019

Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

motor neuron axon guidance

1 reference

8 April 2019

Frazzled regulation of myosin II activity in the Drosophila embryonic CNS.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

regulation of actin polymerization or depolymerization

1 reference

8 April 2019

Epithelial fusions in the embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

positive regulation of lamellipodium assembly

TAS

1 reference

8 April 2019

Distinct effects of Abelson kinase mutations on myocytes and neurons in dissociated Drosophila embryonic cultures: mimicking of high temperature

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

negative regulation of neuron projection development

1 reference

8 April 2019

Distinct effects of Abelson kinase mutations on myocytes and neurons in dissociated Drosophila embryonic cultures: mimicking of high temperature

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

axon midline choice point recognition

1 reference

8 April 2019

Abelson tyrosine kinase is required to transduce midline repulsive cues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

peptidyl-tyrosine phosphorylation

3 references

8 April 2019

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

8 April 2019

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

branchiomotor neuron axon guidance

1 reference

8 April 2019

Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

regulation of protein stability

IBA

1 reference

8 April 2019

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

regulation of protein localization

1 reference

8 April 2019

The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

peptidyl-tyrosine autophosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

regulation of cell population proliferation

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

negative regulation of synaptic assembly at neuromuscular junction

IBA

1 reference

8 April 2019

Abi plays an opposing role to Abl in Drosophila axonogenesis and synaptogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

protein autophosphorylation

1 reference

8 April 2019

A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

positive regulation of protein export from nucleus

1 reference

8 April 2019

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.

compound eye development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

Abelson, enabled, and p120 catenin exert distinct effects on dendritic morphogenesis in Drosophila

IGI

dendrite morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

photoreceptor cell axon guidance

1 reference

8 April 2019

Abelson kinase regulates epithelial morphogenesis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila

regulation of cell shape

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00522

tyrosine-protein kinase, active site

has part(s)

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

protein kinase domain

1 reference

F-actin binding

1 reference

protein kinase, ATP binding site

1 reference

SH3 domain

1 reference

SH2 domain

1 reference

Tyrosine-protein kinase ABL, SH2 domain

1 reference