Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design (Q30043830)

10 September 2018

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24 September 2018

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14 December 2018

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18 December 2018

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20 December 2018

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20 December 2018

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20 December 2018

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20 December 2018

1 reference

1 reference

4

Alexander G Maier

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Sebastian A. Mikolajczak

Sebastian A Mikolajczak

14

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Alan Frederick Cowman

16

Alan F Cowman

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Takafumi Tsuboi

Takafumi Tsuboi

10

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Stefan H I Kappe

17

Stefan H I Kappe

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D. Gray Heppner

12

Donald G Heppner

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author name string

Kelley M VanBuskirk

1

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Matthew T O'Neill

2

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Patricia De La Vega

3

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Urszula Krzych

5

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Jack Williams

6

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Megan G Dowler

7

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John B Sacci

8

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Niwat Kangwanrangsan

9

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Norman M Kneteman

11

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Brant A Murdock

13

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Ahmed S I Aly

Proceedings of the National Academy of Sciences of the United States of America

15

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language of work or name

English

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publication date

4 August 2009

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published in

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volume

106

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issue

31

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page(s)

13004-9

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cites work

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Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

25 May 2017

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Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte

25 May 2017

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An atypical mitogen-activated protein kinase controls cytokinesis and flagellar motility during male gamete formation in a malaria parasite

25 May 2017

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The global distribution of clinical episodes of Plasmodium falciparum malaria

25 May 2017

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Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

25 May 2017

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Hepatitis C virus replication in mice with chimeric human livers

25 May 2017

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Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

25 May 2017

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Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

25 May 2017

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Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity

25 May 2017

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Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

3 June 2018

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Wheat germ cell-free system-based production of malaria proteins for discovery of novel vaccine candidates

3 June 2018

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Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells

3 June 2018

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Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells

3 June 2018

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Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

3 June 2018

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Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection

3 June 2018

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Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax.

3 June 2018

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Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial

3 June 2018

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Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

3 June 2018

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Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

3 June 2018

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Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine

3 June 2018

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Exploring the transcriptome of the malaria sporozoite stage

3 June 2018

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Genes necessary for expression of a virulence determinant and for transmission of Plasmodium falciparum are located on a 0.3-megabase region of chromosome 9.

3 June 2018

1 reference

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Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites

3 June 2018

1 reference

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Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax

3 June 2018

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Letter: Sporozoite induced immunity in man against an Ethiopian strain of Plasmodium falciparum

3 June 2018

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Immunization of man against sporozite-induced falciparum malaria

3 June 2018

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Chromosome size polymorphisms in Plasmodium falciparum can involve deletions and are frequent in natural parasite populations

3 June 2018

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Multiple antigen peptide. A novel approach to increase detection sensitivity of synthetic peptides in solid-phase immunoassays

3 June 2018

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Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion

3 June 2018

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Malaria Sporozoites Release Circumsporozoite Protein from Their Apical End and Translocate It along Their Surface

3 June 2018

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Cultivation of malarial parasites

3 June 2018

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Functional characterization of both MAP kinases of the human malaria parasite Plasmodium falciparum by reverse genetics

3 June 2018

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Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714279

L-FABP is a critical host factor for successful malaria liver stage development.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714279

Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human livers

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714279

Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714279

Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714279

Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination

26 November 2018

1 reference

12 December 2020

Transfection of the human malaria parasite Plasmodium falciparum

1 reference

12 December 2020

Entry of Plasmodium Berghei Sporozoites into Cultured Cells, and Their Transformation into Trophozoites

1 reference

12 December 2020

Purification of mature-stage Plasmodium falciparum by gelatine flotation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0906387106

1 reference

ADS bibcode

2009PNAS..10613004V

0 references

1 reference

1 reference

PubMed publication ID

19625622

1 reference