Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial (Q30053056)

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scientific article (publication date: November 2012)

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English	Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial	scientific article (publication date: November 2012)

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scholarly article

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Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial (English)

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DOI.org query endpoint

https://doi.org/10.1016%2FS0140-6736%2812%2961769-3

25 May 2017

phase III clinical trial

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relapsing-remitting multiple sclerosis

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multiple sclerosis

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Hans-Peter Hartung

6

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Hans-Peter Hartung

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DOI.org query endpoint

25 May 2017

Gavin Giovannoni

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Gavin Giovannoni

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25 May 2017

Howard L. Weiner

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object named as

Howard L Weiner

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https://doi.org/10.1016%2FS0140-6736%2812%2961769-3

25 May 2017

Ivana Kovářová

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author name string

Jeffrey A Cohen

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https://doi.org/10.1016%2FS0140-6736%2812%2961769-3

25 May 2017

Alasdair J Coles

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https://doi.org/10.1016%2FS0140-6736%2812%2961769-3

25 May 2017

Douglas L Arnold

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25 May 2017

Christian Confavreux

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https://doi.org/10.1016%2FS0140-6736%2812%2961769-3

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Edward J Fox

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Eva Havrdova

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Krzysztof W Selmaj

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Elizabeth Fisher

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25 May 2017

Vesna V Brinar

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25 May 2017

Miroslav Stojanovic

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Bella I Ertik

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Stephen L Lake

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David H Margolin

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Michael A Panzara

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D Alastair S Compston

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language of work or name

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publication date

November 2012

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25 May 2017

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380

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9856

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1819-1828

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25 May 2017

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis.

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7 January 2021

based on heuristic

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Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis

1 reference

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7 January 2021

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Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

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7 January 2021

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The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.

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7 January 2021

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Alemtuzumab vs. interferon beta-1a in early multiple sclerosis

1 reference

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7 January 2021

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Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 clinical trial

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7 January 2021

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Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

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7 January 2021

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Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

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7 January 2021

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Development of a multiple sclerosis functional composite as a clinical trial outcome measure

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7 January 2021

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Use of the multiple sclerosis functional composite as an outcome measure in a phase 3 clinical trial.

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7 January 2021

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Neutralization of the biological activity of cytokines and other protein effectors by antibody: theoretical formulation of antibody titration curves in relation to antibody affinity.

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Natalizumab plus interferon beta-1a for relapsing multiple sclerosis

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Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial

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Comparison of subcutaneous interferon beta-1a with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): a multicentre, randomised, parallel, open-label trial

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Statistical methods for the analysis of relapse data in MS clinical trials

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Two-Sample Asymptotically Distribution-Free Tests for Incomplete Multivariate Observations

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Some large-sample distribution-free estimators and tests for multivariate partially incomplete data from two populations.

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A randomized, double-blind, dose-comparison study of weekly interferon beta-1a in relapsing MS

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250 microg or 500 microg interferon beta-1b versus 20 mg glatiramer acetate in relapsing-remitting multiple sclerosis: a prospective, randomised, multicentre study

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

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Phase III dose-comparison study of glatiramer acetate for multiple sclerosis.

1 reference

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Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

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Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study

1 reference

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Association between immediate initiation of intramuscular interferon beta-1a at the time of a clinically isolated syndrome and long-term outcomes: a 10-year follow-up of the Controlled High-Risk Avonex Multiple Sclerosis Prevention Study in Ongoing

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Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model.

1 reference

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Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients.

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Prevalence of incidental thyroid cancer and its ultrasonographic features in subcentimeter thyroid nodules of patients with hyperthyroidism

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Hashimoto's thyroiditis is not associated with increased risk of thyroid cancer in patients with thyroid nodules: a single-center prospective study

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