Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity (Q30155965)

23 September 2017

Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity (English)

1 reference

23 September 2017

Zachary B Hill

1

1 reference

23 September 2017

B Gayani K Perera

series ordinal

2

1 reference

23 September 2017

Dustin J Maly

series ordinal

3

1 reference

23 September 2017

9 November 2010

1 reference

23 September 2017

1 reference

23 September 2017

7

1 reference

23 September 2017

2

1 reference

23 September 2017

447-456

1 reference

Affinity reagents that target a specific inactive form of protein kinases

23 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

A chemical genetic method for generating bivalent inhibitors of protein kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

A quantitative analysis of kinase inhibitor selectivity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Encodable activators of SRC family kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Acquisition of a "Group A"-selective Src kinase inhibitor via a global targeting strategy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Insights into human Lck SH3 domain binding specificity: different binding modes of artificial and native ligands

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

High yield bacterial expression of active c-Abl and c-Src tyrosine kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Dual tyrosine kinase inhibitors in chronic myeloid leukemia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Labeling of fusion proteins with synthetic fluorophores in live cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

The protein kinase complement of the human genome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Designing bisubstrate analog inhibitors for protein kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Protein kinases--the major drug targets of the twenty-first century?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Synthesis and applications of chemical probes for human O6-alkylguanine-DNA alkyltransferase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Oncogenic kinase signalling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Molecular rulers: an assessment of distance and spatial relationships of Src tyrosine kinase Sh2 and active site regions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Signaling--2000 and beyond

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Rational design of specific high-affinity peptide ligands for the Abl-SH3 domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Design, synthesis, and characterization of an ATP-peptide conjugate inhibitor of protein kinase A.

3 June 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: molecular yardsticks for analyzing catalytic mechanism and inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Increasing the kinase specificity of k252a by protein surface recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Stepwise combinatorial evolution of Akt bisubstrate inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

A general method for the covalent labeling of fusion proteins with small molecules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Design, synthesis and characterization of "clickable" 4-anilinoquinazoline kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Studies leading to the identification of ZD1839 (IRESSA): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0MB00108B

Cellular targets of gefitinib

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268058

Design of potent protein kinase inhibitors using the bisubstrate approach

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21060940

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1039/C0MB00108B

1 reference

release_7ivbanss3zd2fahzagjtlusorq

23 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7ivbanss3zd2fahzagjtlusorq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

23 September 2017

PubMed publication ID

21060940

1 reference