ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients. (Q30156959)

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English	ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.	scientific article

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18 January 2020

ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients (English)

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18 January 2020

colorectal cancer

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based on heuristic

inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

neoplastic invasiveness

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based on heuristic

inferred from title

Alessia Galasso

9

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18 January 2020

Jonathan P. Sleeman

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18 January 2020

author name string

T Müller

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18 January 2020

U Stein

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18 January 2020

A Poletti

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18 January 2020

L Garzia

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18 January 2020

M Rothley

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18 January 2020

D Plaumann

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18 January 2020

W Thiele

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18 January 2020

M Bauer

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18 January 2020

P Schlag

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18 January 2020

M Pankratz

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18 January 2020

M Zollo

12

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publication date

15 February 2010

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

2393-2403

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18 January 2020

Identification of a new Pyk2 target protein with Arf-GAP activity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Src-dependent phosphorylation of ASAP1 regulates podosomes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Newest findings on the oldest oncogene; how activated src does it

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

ASAP1, a gene at 8q24, is associated with prostate cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Understanding h-prune biology in the fight against cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

CrkL directs ASAP1 to peripheral focal adhesions.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Expression of multidrug resistance genes MVP, MDR1, and MRP1 determined sequentially before, during, and after hyperthermic isolated limb perfusion of soft tissue sarcoma and melanoma patients.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Association of the Ste20-like kinase (SLK) with the microtubule. Role in Rac1-mediated regulation of actin dynamics during cell adhesion and spreading.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

21 January 2018

Differential immunization identifies PHB1/PHB2 as blood-borne tumor antigens

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.6

31 March 2020

Identifiers

10.1038/ONC.2010.6

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20154719%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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1 reference

Europe PubMed Central

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18 January 2020

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Springer Nature article ID

10.1038/onc.2010.6

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