Galpha12 regulates epithelial cell junctions through Src tyrosine kinases (Q30164599)

9 June 2017

Galpha12 regulates epithelial cell junctions through Src tyrosine kinases (English)

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9 June 2017

Tobias N Meyer

1

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9 June 2017

Jennifer Hunt

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2

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9 June 2017

Catherine Schwesinger

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3

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9 June 2017

Bradley M Denker

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4

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9 June 2017

30 July 2003

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American Journal of Physiology - Cell Physiology

9 June 2017

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9 June 2017

285

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9 June 2017

5

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9 June 2017

C1281-93

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Assembly and sealing of tight junctions: possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin

9 June 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Identification of isoforms of G proteins and PKC that colocalize with tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Protein modules as organizers of membrane structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Role of calcium in tight junction formation between epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Differential localization of G-proteins, G alpha o and G alpha i-1, -2, and -3, in polarized epithelial MDCK cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The transforming activity of activated G alpha 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Secretory activity and oncogenicity of a cell line (MDCK) derived from canine kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Molecular architecture of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The Src family tyrosine kinase is involved in Rho-dependent activation of c-Jun N-terminal kinase by Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Heterotrimeric G proteins: organizers of transmembrane signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

The alpha-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Protein kinase C-alpha activity modulates transepithelial permeability and cell junctions in the LLC-PK1 epithelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Expanding role of G proteins in tight junction regulation: Galpha(s) stimulates TJ assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Differential regulation of COX-2 transcription by Ras- and Rho-family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Critical role for intracellular calcium in tight junction biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Expression of a molecularly cloned human c-src oncogene by using a replication-competent retroviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Multifunctional strands in tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00548.2002

10.1152/AJPCELL.00548.2002

21 January 2018

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DOI

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9 June 2017

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