Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain (Q30165193)

9 June 2017

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain (English)

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9 June 2017

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Steven J Schreiner

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9 June 2017

Anthony P Schiavone

series ordinal

2

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9 June 2017

Thomas E Smithgall

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3

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9 June 2017

language of work or name

English

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publication date

19 September 2002

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Journal of Biological Chemistry

9 June 2017

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9 June 2017

277

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9 June 2017

47

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9 June 2017

45680-45687

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Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.

9 June 2017

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Src family tyrosine kinases and growth factor signaling

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Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

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Selected glimpses into the activation and function of Src kinase

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Role of Src expression and activation in human cancer

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Src inhibitors: drugs for the treatment of osteoporosis, cancer or both?

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Structures of Src-family tyrosine kinases

21 January 2018

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Insights into Src kinase functions: structural comparisons

21 January 2018

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The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204255200

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

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Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204255200

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

21 January 2018

1 reference

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SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts.

21 January 2018

1 reference

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The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

The Stat family in cytokine signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204255200

STAT proteins and transcriptional responses to extracellular signals

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204255200

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Activation and association of Stat3 with Src in v-Src-transformed cell lines

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204255200

Stat3 activation is required for cellular transformation by v-src

21 January 2018

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Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.

21 January 2018

1 reference

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Activation of STAT3 by the c-Fes protein-tyrosine kinase

21 January 2018

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Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck

21 January 2018

1 reference

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Tyrosine phosphorylation enhances the SH2 domain-binding activity of Bcr and inhibits Bcr interaction with 14-3-3 proteins

21 January 2018

1 reference

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SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.

21 January 2018

1 reference

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BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

1 reference

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Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

HIV-1 Nef promotes survival of myeloid cells by a Stat3-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

A target for Src in mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Control of myeloid differentiation and survival by Stats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Three-dimensional structure of the Stat3beta homodimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

21 January 2018

1 reference

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The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

21 January 2018

1 reference

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Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204255200

Regulation of c-SRC activity and function by the adapter protein CAS

21 January 2018

1 reference

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Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions

21 January 2018

1 reference

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Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M204255200

1 reference

9 June 2017

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