The isoform-specific stretch of hSos1 defines a new Grb2-binding domain (Q30168551)

9 June 2017

title

The isoform-specific stretch of hSos1 defines a new Grb2-binding domain (English)

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9 June 2017

Zarich N

1

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9 June 2017

Oliva JL

2

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9 June 2017

Jorge R

3

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9 June 2017

Santos E

4

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9 June 2017

Rojas JM

5

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9 June 2017

language of work or name

English

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publication date

1 November 2000

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9 June 2017

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9 June 2017

volume

19

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9 June 2017

issue

51

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9 June 2017

page(s)

5872-5883

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Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

9 June 2017

cites work

1 reference

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Proteins regulating Ras and its relatives

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The structural basis of the activation of Ras by Sos

21 January 2018

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Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

21 January 2018

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21 January 2018

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Regulation of Sos activity by intramolecular interactions

21 January 2018

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Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

21 January 2018

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The GRB2/Sem-5 adaptor protein

21 January 2018

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Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

21 January 2018

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Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

21 January 2018

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Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

21 January 2018

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Transformation suppressor activity of C3G is independent of its CDC25-homology domain.

21 January 2018

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Signal transduction in T lymphocytes using a conditional allele of Sos

21 January 2018

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Ras effectors and their role in mitogenesis and oncogenesis

21 January 2018

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In vivo functional analysis of the Ras exchange factor son of sevenless

21 January 2018

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Activation of Ras and its downstream extracellular signal-regulated protein kinases by the CDC25 homology domain of mouse Son-of-sevenless 1 (mSos1).

21 January 2018

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The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1)

21 January 2018

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Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells

21 January 2018

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Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylation

21 January 2018

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Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor

21 January 2018

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

21 January 2018

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Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

21 January 2018

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A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.

21 January 2018

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SH3 domains. Minding your p's and q's.

21 January 2018

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Functional Roles for the Pleckstrin and Dbl Homology Regions in the Ras Exchange Factor Son-of-sevenless

21 January 2018

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Signal transduction. How receptors turn Ras on.

21 January 2018

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Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I

21 January 2018

1 reference

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Applications of interaction traps/two-hybrid systems to biotechnology research

21 January 2018

1 reference

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Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

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Protein modules and signalling networks

21 January 2018

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21 January 2018

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Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity

21 January 2018

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Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

21 January 2018

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Identification of a ten-amino acid proline-rich SH3 binding site

21 January 2018

1 reference

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Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1.

21 January 2018

1 reference

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

1 reference

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How receptor tyrosine kinases activate Ras.

21 January 2018

1 reference

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Grb2 SH3 binding to peptides from Sos: evaluation of a general model for SH3-ligand interactions

21 January 2018

1 reference

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Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

21 January 2018

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From Src Homology domains to other signaling modules: proposal of the 'protein recognition code'.

21 January 2018

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Cell cycle-dependent activation of Ras.

21 January 2018

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The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain

21 January 2018

1 reference

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The Grb2 binding domain of mSos1 is not required for downstream signal transduction

21 January 2018

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Binding of Vav to Grb2 through dimerization of Src homology 3 domains

21 January 2018

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Structural basis for the binding of proline-rich peptides to SH3 domains

21 January 2018

1 reference

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Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation

21 January 2018

1 reference

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EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

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The pathway to signal achievement

21 January 2018

1 reference

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A Sos-derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Laser treatment of port-wine stains and hemangiomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203955

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203955

1 reference

Dimensions Publication ID

9 June 2017

1047740454

0 references

1 reference