Mechanisms of diabetes mellitus-induced bone fragility (Q30241947)

12 June 2017

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title

Mechanisms of diabetes mellitus-induced bone fragility (English)

1 reference

12 June 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Bo Abrahamsen

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

5

Ann V Schwartz

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Manju Chandran

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Dominique D Pierroz

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Serge L Ferrari

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

IOF Bone and Diabetes Working Group

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

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23 September 2016

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Nature Reviews Endocrinology

12 June 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27658727%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

4

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1 June 2020

page(s)

208-219

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Older women with diabetes have a higher risk of falls: a prospective study

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Diabetes mellitus is associated with an increased risk of falls in elderly residents of a long-term care facility

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Physical activity, falls, and fractures among older adults: a review of the epidemiologic evidence

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Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures.

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Compromised cortical bone compartment in type 2 diabetes mellitus patients with microvascular disease.

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Trabecular and cortical microstructure and fragility of the distal radius in women

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Volumetric femoral BMD, bone geometry, and serum sclerostin levels differ between type 2 diabetic postmenopausal women with and without fragility fractures

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Advanced glycosylation end products in diabetic renal and vascular disease

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Glycation endproducts in osteoporosis--is there a pathophysiologic importance?

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31 March 2020

Type 2 diabetes and bone

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Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls

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Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes

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Advanced glycation endproducts stimulate interleukin-6 production by human bone-derived cells

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Role of advanced glycation end products in adynamic bone disease in patients with diabetic nephropathy.

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Role of nonenzymatic glycosylation of type I collagen in diabetic osteopenia

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Advanced glycation end-products attenuate human mesenchymal stem cells and prevent cognate differentiation into adipose tissue, cartilage, and bone

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Advanced glycation endproducts interefere with integrin-mediated osteoblastic attachment to a type-I collagen matrix

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Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury

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Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes

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Effects of high glucose and high insulin concentrations on osteoblast function in vitro

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Extracellular glucose influences osteoblast differentiation and c-Jun expression

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Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways

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Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation

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Glucose-induced inhibition of in vitro bone mineralization

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How metabolic acidosis and oxidative stress alone and interacting may increase the risk of fracture in diabetic subjects

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High glucose induces adipogenic differentiation of muscle-derived stem cells

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High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study

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Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells

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The effects of local insulin delivery on diabetic fracture healing

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Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.

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Effect of advanced glycation endproducts on the secretion of insulin-like growth factor-I and its binding proteins: role in osteoblast development

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Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells

31 March 2020

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Serum insulin-like growth factor-I is a marker for assessing the severity of vertebral fractures in postmenopausal women with type 2 diabetes mellitus

31 March 2020

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Amylin and adrenomedullin: novel regulators of bone growth.

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Inhibition of osteoblast differentiation by tumor necrosis factor-alpha

31 March 2020

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M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase

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From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis

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31 March 2020

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FFAs-ROS-ERK/P38 pathway plays a key role in adipocyte lipotoxicity on osteoblasts in co-culture

31 March 2020

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Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes

31 March 2020

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Marrow fat and bone--new perspectives

31 March 2020

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White, brown, beige/brite: different adipose cells for different functions?

31 March 2020

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Inducible brown adipose tissue, or beige fat, is anabolic for the skeleton

31 March 2020

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Reduced Incretin Effect in Type 2 Diabetes

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Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor

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Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow

31 March 2020

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Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes.

31 March 2020

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Exendin-4, a glucagon-like peptide-1 receptor agonist, prevents osteopenia by promoting bone formation and suppressing bone resorption in aged ovariectomized rats.

31 March 2020

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Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study

31 March 2020

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Diabetes and risk of fracture-related hospitalization: the Atherosclerosis Risk in Communities Study

31 March 2020

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Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial

31 March 2020

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Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes

31 March 2020

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Weight loss, exercise, or both and physical function in obese older adults

31 March 2020

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Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones

31 March 2020

1 reference

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Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training

31 March 2020

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Oral anti-diabetic drugs and fracture risk, cut to the bone: safe or dangerous? A narrative review

31 March 2020

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Bone fractures and hypoglycemic treatment in type 2 diabetic patients: a case-control study

31 March 2020

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Metformin enhances the differentiation and mineralization of osteoblastic MC3T3-E1 cells via AMP kinase activation as well as eNOS and BMP-2 expression

31 March 2020

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A cohort study of thiazolidinediones and fractures in older adults with diabetes

31 March 2020

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Durability of the efficacy and safety of alogliptin compared with glipizide in type 2 diabetes mellitus: a 2-year study.

31 March 2020

1 reference

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PPARγ: a circadian transcription factor in adipogenesis and osteogenesis

31 March 2020

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Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis

31 March 2020

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Thiazolidinedione use and the risk of fractures.

31 March 2020

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Risk of fracture with thiazolidinediones: an updated meta-analysis of randomized clinical trials

31 March 2020

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Use of glucagon-like peptide-1 receptor agonists and bone fractures: a meta-analysis of randomized clinical trials.

31 March 2020

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Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials

31 March 2020

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Dipeptidyl peptidase-4 inhibitors and bone fractures: a meta-analysis of randomized clinical trials

31 March 2020

1 reference

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Incidence of Fractures in Patients With Type 2 Diabetes in the SAVOR-TIMI 53 Trial

31 March 2020

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The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia.

31 March 2020

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Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2016.153

Evaluation of Bone Mineral Density and Bone Biomarkers in Patients With Type 2 Diabetes Treated With Canagliflozin

31 March 2020

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Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus

31 March 2020

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

31 March 2020

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U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group

31 March 2020

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

31 March 2020

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Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

31 March 2020

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Increasing adiposity is associated with higher adipokine levels and lower bone mineral density in obese older adults

31 March 2020

1 reference

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Circulating sclerostin associated with vertebral bone marrow fat in older men but not women

31 March 2020

1 reference

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Effect of ghrelin on bone mass density: the InChianti study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2016.153