Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation (Q30309445)

16 June 2017

Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation (English)

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16 June 2017

Rajesh Kumar

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author name string

Amy L Eastwood

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2

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16 June 2017

Milton L Brown

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3

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16 June 2017

Gordon W Laurie

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4

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16 June 2017

language of work or name

English

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publication date

1 June 2002

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Journal of Molecular Biology

16 June 2017

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16 June 2017

319

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16 June 2017

3

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16 June 2017

593-602

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Coeliac disease in the year 2000: exploring the iceberg

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Molecular basis of celiac disease

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Identification of tissue transglutaminase as the autoantigen of celiac disease

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Celiac disease: strongly heritable, oligogenic, but genetically complex

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Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked coeliac disease susceptibility genes

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Genetic contribution of the HLA region to the familial clustering of coeliac disease.

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Linkage analysis of candidate regions for coeliac disease genes

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A pedigree-based linkage study of coeliac disease: failure to replicate previous positive findings

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Genome search in celiac disease.

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Human genome search in celiac disease using gliadin cDNA as probe

7 January 2021

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Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease.

7 January 2021

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Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition

7 January 2021

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HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope

7 January 2021

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The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase

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In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope.

7 January 2021

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Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin

7 January 2021

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Human jejunal transglutaminase: demonstration of activity, enzyme kinetics and substrate specificity with special relation to gliadin and coeliac disease

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A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death

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Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

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Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients

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Amino acid substitution matrices from protein blocks

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Binding of Peptides from the N-Terminal Region of α-Gliadin to the Celiac Disease-Associated HLA-DQ2 Molecule Assessed in Biochemical and T Cell Assays

7 January 2021

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The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule

7 January 2021

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Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule

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Role of general and gene-specific cofactors in the regulation of eukaryotic transcription

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Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal and activated transcription

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Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation

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Protease footprinting analysis of ternary complex formation by human TFIIA.

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Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity

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A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA

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Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

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Novel structural features of the human histocompatibility molecules HLA-DQ as revealed by modeling based on the published structure of the related molecule HLA-DR

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Improved tools for biological sequence comparison

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Rapid detection of deletion, insertion, and substitution mutations via heteroduplex analysis using capillary- and microchip-based electrophoresis

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Evidence for a High Frequency of Simultaneous Double-Nucleotide Substitutions

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cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland

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Cloning and characterization of RAP250, a novel nuclear receptor coactivator

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Quantitative analysis of the T cell repertoire that escapes negative selection

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T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation

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Pathology of CAG repeat diseases

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Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease

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Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

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The neurology and neuropathology of coeliac disease

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Positional cloning of the APECED gene

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JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

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An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland

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Genome-wide linkage analysis of Scandinavian affected sib-pairs supports presence of susceptibility loci for celiac disease on chromosomes 5 and 11

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Genomewide linkage analysis of celiac disease in Finnish families

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10.1016/S0022-2836(02)00366-2

7 January 2021

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DOI

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16 June 2017

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