Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy (Q30310231)

16 June 2017

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title

Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy (English)

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16 June 2017

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David W Mullins

5

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Victor H Engelhard

object named as

Victor H Engelhard

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author name string

Timothy N J Bullock

2

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PubMed ID

12445287

16 June 2017

Teresa A Colella

3

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PubMed ID

12445287

16 June 2017

Stacey L Sheasley

4

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16 June 2017

1 October 2002

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16 June 2017

Immunological Reviews

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16 June 2017

188

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16 June 2017

136-146

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The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

16 June 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Identification of gp100-derived, melanoma-specific cytotoxic T-lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Mass-spectrometric evaluation of HLA-A*0201-associated peptides identifies dominant naturally processed forms of CTL epitopes from MART-1 and gp100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Generation of T-cell immunity to a murine melanoma using MART-1-engineered dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Immune responses to the HLA-A*0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A*0201-transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

The density of peptides displayed by dendritic cells affects immune responses to human tyrosinase and gp100 in HLA-A2 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Manipulation of avidity to improve effectiveness of adoptively transferred CD8(+) T cells for melanoma immunotherapy in human MHC class I-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Relevance of the tumor antigen in the validation of three vaccination strategies for melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Analogues of CTL epitopes with improved MHC class-I binding capacity elicit anti-melanoma CTL recognizing the wild-type epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Clonal expansion of Melan A-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Molecular analysis of viable spontaneous and radiation-induced albino (c)-locus mutations in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Murine tyrosinase expressed by a T7 vector in bone marrow-derived dendritic progenitors effectively prevents and eradicates melanoma tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Isolation of naturally processed peptides recognized by cytolytic T lymphocytes (CTL) on human melanoma cells in association with HLA-A2.1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Vitiligo in patients with metastatic melanoma: a good prognostic sign

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Direct identification of tumor-associated peptide antigens.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Differences and similarities in the A2.1-restricted cytotoxic T cell repertoire in humans and human leukocyte antigen-transgenic mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Tyrosinase, the key enzyme in melanin synthesis, is expressed in murine brain.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Tyrosinase gene expression in human tissues

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Genetic immunization of mice with human tyrosinase-related protein 2: implications for the immunotherapy of melanoma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18812.X

7 January 2021

10.1034/J.1600-065X.2002.18812.X

Identifiers

DOI

1 reference

16 June 2017

1 reference

PubMed ID

12445287