The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90. (Q30319867)

17 June 2017

The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90. (English)

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17 June 2017

Frank Edlich

1

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17 June 2017

Frank Erdmann

2

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17 June 2017

Franziska Jarczowski

3

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17 June 2017

Marie-Christine Moutty

4

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17 June 2017

Matthias Weiwad

5

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17 June 2017

Gunter Fischer

6

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17 June 2017

language of work or name

English

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publication date

22 March 2007

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Journal of Biological Chemistry

17 June 2017

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17 June 2017

282

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17 June 2017

21

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17 June 2017

15341-15348

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Regulation of peptide bond cis/trans isomerization by enzyme catalysis and its implication in physiological processes

17 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

FKBPs: at the crossroads of folding and transduction.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611594200

Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

A reassessment of the inhibitory capacity of human FKBP38 on calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

The specific FKBP38 inhibitor N-(N',N'-dimethylcarboxamidomethyl)cycloheximide has potent neuroprotective and neurotrophic properties in brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

The role of chaperone proteins in the aryl hydrocarbon receptor core complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Localization and characterization of the 86- and 84-kDa heat shock proteins in Hepa 1c1c7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Coordinated ATP hydrolysis by the Hsp90 dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

The beta-isoform of heat shock protein hsp-90 is structurally related with human microtubule-interacting protein Mip-90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Calmodulin in action: diversity in target recognition and activation mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Heat-shock protein 90 augments neuronal nitric oxide synthase activity by enhancing Ca2+/calmodulin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Calmodulin-dependent and -independent activation of endothelial nitric-oxide synthase by heat shock protein 90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

FKBP ligands as novel therapeutics for neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Two structures of cyclophilin 40: folding and fidelity in the TPR domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Molecular recognition via coupled folding and binding in a TPR domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Heat shock proteins 70 and 90 increase calcineurin activity in vitro through calmodulin-dependent and independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Heat shock pretreatment inhibited the release of Smac/DIABLO from mitochondria and apoptosis induced by hydrogen peroxide in cardiomyocytes and C2C12 myogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611594200

21 January 2018

Identifiers

DOI

10.1074/JBC.M611594200

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17 June 2017

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