Cdc25 as a potential target of anticancer agents. (Q30326904)

18 June 2017

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title

Cdc25 as a potential target of anticancer agents. (English)

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18 June 2017

Eckstein JW

1

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18 June 2017

1 May 2000

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Investigational New Drugs

18 June 2017

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18 June 2017

18

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18 June 2017

2

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18 June 2017

149-156

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Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

18 June 2017

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12 December 2020

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

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12 December 2020

Structural determination of stevastelins, novel depsipeptides from Penicillium sp

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12 December 2020

The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications

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12 December 2020

RNA-Mediated interference of a cdc25 homolog in Caenorhabditis elegans results in defects in the embryonic cortical membrane, meiosis, and mitosis

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12 December 2020

Structure and function of the protein tyrosine phosphatases

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12 December 2020

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

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12 December 2020

Antisense phosphorothioate oligonucleotides specifically down-regulate cdc25B causing S-phase delay and persistent antiproliferative effects.

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12 December 2020

CDC25 phosphatases as potential human oncogenes

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12 December 2020

Alkyl and alkoxyethyl antineoplastic phospholipids

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12 December 2020

Naphthoquinone analogs as inactivators of cdc25 phosphatase

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12 December 2020

Cell cycle: on target with Myc.

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12 December 2020

Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine

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12 December 2020

C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding

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12 December 2020

Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate

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12 December 2020

Checkpoints on the road to mitosis

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12 December 2020

Cdc25A is a novel phosphatase functioning early in the cell cycle

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12 December 2020

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics

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12 December 2020

Synthesis and antitumor activity of some new substituted quinolin-4-one and 1,7-naphthyridin-4-one analogs

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12 December 2020

Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A

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12 December 2020

Synthesis of vitamin K-dependent proteins

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12 December 2020

Overexpression of cdc25A and cdc25B is frequent in primary non-small cell lung cancer but is not associated with overexpression of c-myc

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12 December 2020

Vitamin K3 inhibits growth of human hepatoma HepG2 cells by decreasing activities of both p34cdc2 kinase and phosphatase

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12 December 2020

Checkpoint on the nuclear frontier

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12 December 2020

14-3-3 proteins act as negative regulators of the mitotic inducer Cdc25 in Xenopus egg extracts

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12 December 2020

RK-682, a potent inhibitor of tyrosine phosphatase, arrested the mammalian cell cycle progression at G1phase

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12 December 2020

A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation

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12 December 2020

Dnacin A1 and dnacin B1 are antitumor antibiotics that inhibit cdc25B phosphatase activity

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12 December 2020

cdc25 cell cycle-activating phosphatases and c-myc expression in human non-Hodgkin's lymphomas

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12 December 2020

Cdc25 cell-cycle phosphatase as a target of c-myc

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12 December 2020

Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel

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12 December 2020

Protein-tyrosine phosphatases: structure, mechanism, and inhibitor discovery

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12 December 2020

Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics

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12 December 2020

Arrest at the G2/M transition of the cell cycle by protein-tyrosine phosphatase inhibition: studies on a neuronal and a glial cell line

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12 December 2020

Hexadecylphosphocholine, a new ether lipid analogue. Studies on the antineoplastic activity in vitro and in vivo

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12 December 2020

Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization

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12 December 2020

The four cdc25 genes from the nematode Caenorhabditis elegans

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12 December 2020

5-substituted 2-bromoindolo[3,2-b]quinoxalines. A class of potential antitumor agents with cdc25 phosphatase inhibitory properties

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12 December 2020

Overexpression of cyclin-dependent kinase-activating CDC25B phosphatase in human gastric carcinomas.

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12 December 2020

In vivo inactivation of phosphotyrosine protein phosphatases by nitric oxide.

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12 December 2020

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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12 December 2020

Cdc25 protein phosphatases in cell proliferation

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12 December 2020

Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatase.

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12 December 2020

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

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12 December 2020

Overexpression of CDC25A and CDC25B in head and neck cancers

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12 December 2020

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

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12 December 2020

Identification of an essential acidic residue in Cdc25 protein phosphatase and a general three-dimensional model for a core region in protein phosphatases

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12 December 2020

Phosphatases and tumorigenesis

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12 December 2020

Kinetic analysis of the catalytic domain of human cdc25B.

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12 December 2020

cdc25+ functions as an inducer in the mitotic control of fission yeast.

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12 December 2020

A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain

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12 December 2020

Cell growth inhibition by a novel vitamin K is associated with induction of protein tyrosine phosphorylation

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12 December 2020

Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy,isolation, and characterization.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1342

Identifiers

DOI

10.1023/A:1006377913494

1 reference

PubMed ID

10857994

Dimensions Publication ID

18 June 2017

0 references

1 reference

PubMed ID

10857994