Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation. (Q30351081)

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31 December 2019

title

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation (English)

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31 December 2019

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31 December 2019

author name string

S Cai

1

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31 December 2019

J Khoo

2

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31 December 2019

S Mussa

3

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31 December 2019

N J Alp

4

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31 December 2019

publication date

21 July 2005

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31 December 2019

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31 December 2019

volume

48

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31 December 2019

issue

9

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31 December 2019

page(s)

1933-1940

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Mechanisms underlying endothelial dysfunction in diabetes mellitus

31 December 2019

cites work

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Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin

21 January 2018

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Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase

21 January 2018

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Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase

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Mammalian nitric oxide synthases

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Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms

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Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.

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Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process

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Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants

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Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin

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Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

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Experimental study of balloon-expandable metallic vena caval stents in rabbits

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Oxygen reduction by nitric-oxide synthases

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Tetrahydrobiopterin biosynthesis, regeneration and functions

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Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus

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Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

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Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

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Effect of tetrahydrobiopterin on endothelial function in canine middle cerebral arteries

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GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation

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Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III.

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EPR quantification of vascular nitric oxide production in genetically modified mouse models

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Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus

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Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression

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Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats

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Guanabenz-mediated inactivation and enhanced proteolytic degradation of neuronal nitric-oxide synthase

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Tetrahydrobiopterin inhibits monomerization and is consumed during catalysis in neuronal NO synthase

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Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

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12 December 2020

Domains of macrophage N(O) synthase have divergent roles in forming and stabilizing the active dimeric enzyme

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12 December 2020

Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?

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Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

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12 December 2020

Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation.

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Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

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Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors

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Cellular and molecular mechanisms of endothelial cell dysfunction

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Mammalian nitric oxide synthases

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Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer

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Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.

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S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity

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Exogenous tetrahydrobiopterin causes endothelium-dependent contractions in isolated canine basilar artery

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Ubiquitination of neuronal nitric-oxide synthase in vitro and in vivo

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12 December 2020

Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

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12 December 2020

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

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12 December 2020

Tetrahydrobiopterin and endothelial nitric oxide synthase activity

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12 December 2020

10.1007/S00125-005-1857-5

Identifiers

DOI

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Dimensions Publication ID

31 December 2019

1044252544

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