DNA vaccines for HIV: challenges and opportunities. (Q30357322)

20 June 2017

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title

DNA vaccines for HIV: challenges and opportunities. (English)

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20 June 2017

David A Hokey

1

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20 June 2017

David B Weiner

series ordinal

2

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20 June 2017

publication date

10 October 2006

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Seminars in Immunopathology

20 June 2017

published in

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20 June 2017

volume

28

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20 June 2017

issue

3

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20 June 2017

page(s)

267-279

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Electroporation enables plasmid vaccines to elicit CD8+ T cell responses in the absence of CD4+ T cells.

20 June 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

A role for class A scavenger receptor in dendritic cell nibbling from live cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Developing DNA vaccines that call to dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Induction of positive cellular and humoral immune responses by a prime-boost vaccine encoded with simian immunodeficiency virus gag/pol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

Increased DNA vaccine delivery and immunogenicity by electroporation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-006-0046-Z

DNA vaccines against human immunodeficiency virus type 1 in the past decade

21 January 2018

1 reference

12 December 2020

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

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12 December 2020

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages

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12 December 2020

Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines.

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12 December 2020

Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy

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12 December 2020

Apoptosis-mediated enhancement of DNA-raised immune responses by mutant caspases

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12 December 2020

Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins

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12 December 2020

Helping the CD8(+) T-cell response

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12 December 2020

Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses

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12 December 2020

A noninfectious simian/human immunodeficiency virus DNA vaccine that protects macaques against AIDS.

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12 December 2020

Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips".

1 reference

12 December 2020

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge

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12 December 2020

DNA vaccines: immunology, application, and optimization*

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12 December 2020

Electric pulses increase the immunogenicity of an influenza DNA vaccine injected intramuscularly in the mouse

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12 December 2020

Natural adjuvants: endogenous activators of dendritic cells

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12 December 2020

Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

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12 December 2020

Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity

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12 December 2020

Microneedles for transdermal drug delivery

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12 December 2020

Dendritic cells containing apoptotic melanoma cells prime human CD8+ T cells for efficient tumor cell lysis

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12 December 2020

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.

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12 December 2020

Dead or alive: immunogenicity of human melanoma cells when presented by dendritic cells

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12 December 2020

Studies using a viral challenge and CD8 T cell depletions on the roles of cellular and humoral immunity in the control of an SHIV-89.6P challenge in DNA/MVA-vaccinated macaques.

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12 December 2020

Transcutaneous immunization: a human vaccine delivery strategy using a patch

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12 December 2020

Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

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12 December 2020

Topical gene delivery to murine skin

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12 December 2020

Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.

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12 December 2020

Direct transfection and activation of human cutaneous dendritic cells

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12 December 2020

Therapeutic potential of Toll-like receptor 9 activation

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12 December 2020

Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis

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12 December 2020

T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

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12 December 2020

Novel simian immunodeficiency virus CTL epitopes restricted by MHC class I molecule Mamu-B*01 are highly conserved for long term in DNA/MVA-vaccinated, SHIV-challenged rhesus macaques

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12 December 2020

In vivo electroporation for gene therapy

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12 December 2020

Electroporation improves the efficacy of DNA vaccines in large animals

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12 December 2020

RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs

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12 December 2020

Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization in a mouse model

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12 December 2020

Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen

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12 December 2020

Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus

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12 December 2020

Genetic immunization is a simple method for eliciting an immune response

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12 December 2020

Signature for long-term vaccine-mediated control of a Simian and human immunodeficiency virus 89.6P challenge: stable low-breadth and low-frequency T-cell response capable of coproducing gamma interferon and interleukin-2.

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12 December 2020

DNA-based immunization by in vivo transfection of dendritic cells

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12 December 2020

Multiple effects of codon usage optimization on expression and immunogenicity of DNA candidate vaccines encoding the human immunodeficiency virus type 1 Gag protein

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12 December 2020

Protective immunity induced by oral immunization with a rotavirus DNA vaccine encapsulated in microparticles

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12 December 2020

Cytotoxic T lymphocyte activation by cross-priming

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12 December 2020

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

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12 December 2020

DermaVir, a novel HIV immunisation technology

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12 December 2020

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

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12 December 2020

Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

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12 December 2020

Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates

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12 December 2020

Advances in vaccine adjuvants

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12 December 2020

A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules

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12 December 2020

Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene

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12 December 2020

Elicitation of high-frequency cytotoxic T-lymphocyte responses against both dominant and subdominant simian-human immunodeficiency virus epitopes by DNA vaccination of rhesus monkeys

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12 December 2020

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

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12 December 2020

Cellular protein is the source of cross-priming antigen in vivo

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12 December 2020

Restoring function in exhausted CD8 T cells during chronic viral infection

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12 December 2020

Loss of reactivity of vaccine-induced CD4 T cells in immunized monkeys after SIV/HIV challenge.

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12 December 2020

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

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12 December 2020

Introduction of soluble protein into the class I pathway of antigen processing and presentation

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12 December 2020

Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine

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12 December 2020

Next generation DNA vaccines for HIV-1.

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12 December 2020

Immune responses and protection obtained by oral immunization with rotavirus VP4 and VP7 DNA vaccines encapsulated in microparticles

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12 December 2020

SIV DNA vaccine co-administered with IL-12 expression plasmid enhances CD8 SIV cellular immune responses in cynomolgus macaques

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12 December 2020

Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression

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12 December 2020

Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines.

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12 December 2020

Intradermal DNA immunization by using jet-injectors in mice and monkeys

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12 December 2020

Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids.

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12 December 2020

Enhancement of DNA vaccine potency by electroporation in vivo

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12 December 2020

Adjuvant activity of CpG oligodeoxynucleotides

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12 December 2020

Heterologous human immunodeficiency virus type 1 priming-boosting immunization strategies involving replication-defective adenovirus and poxvirus vaccine vectors

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12 December 2020

Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo

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12 December 2020

Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag

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12 December 2020

The dendritic cell system and its role in immunogenicity

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12 December 2020

Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3.

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12 December 2020

Molecular identification of a danger signal that alerts the immune system to dying cells

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12 December 2020

In vivo electroporation improves immune responses to DNA vaccination in sheep

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12 December 2020

Tumor cell loaded type-1 polarized dendritic cells induce Th1-mediated tumor immunity

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12 December 2020

Equipotent generation of protective antitumor immunity by various methods of dendritic cell loading with whole cell tumor antigens

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12 December 2020

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations

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12 December 2020

Enhancement of human immunodeficiency virus type 1-DNA vaccine potency through incorporation of T-helper 1 molecular adjuvants

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

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12 December 2020

Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device

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12 December 2020

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

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12 December 2020

DNA vaccines encoding interleukin-8 and RANTES enhance antigen-specific Th1-type CD4(+) T-cell-mediated protective immunity against herpes simplex virus type 2 in vivo

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12 December 2020

Augmentation and suppression of immune responses to an HIV-1 DNA vaccine by plasmid cytokine/Ig administration.

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12 December 2020

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity

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12 December 2020

Vaccination onto bare skin

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12 December 2020

The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses

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12 December 2020

Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF

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12 December 2020

Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines

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12 December 2020

Improving DNA vaccines targeting viral infection

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12 December 2020

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

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12 December 2020

Anti-HBV immune responses in rhesus macaques elicited by electroporation mediated DNA vaccination

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12 December 2020

Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe

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12 December 2020

Comparative analysis of necrotic and apoptotic tumor cells as a source of antigen(s) in dendritic cell-based immunization.

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12 December 2020

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

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12 December 2020

DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication

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12 December 2020

Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization.

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12 December 2020

10.1007/S00281-006-0046-Z

Identifiers

DOI

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Dimensions Publication ID

20 June 2017

1044564638

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