Microbicides and other topical agents in the prevention of HIV and sexually transmitted infections. (Q30359545)

20 June 2017

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title

Microbicides and other topical agents in the prevention of HIV and sexually transmitted infections. (English)

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sexually transmitted infection

20 June 2017

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prevention of HIV/AIDS

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3

Vincent Piguet

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20 June 2017

1

Damjan S Nikolic

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20 June 2017

Eduardo Garcia

2

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20 June 2017

publication date

1 February 2007

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Expert Review of Anti-infective Therapy

20 June 2017

published in

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20 June 2017

volume

5

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20 June 2017

issue

1

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20 June 2017

page(s)

77-88

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HIV/AIDS in women: an expanding epidemic

20 June 2017

cites work

1 reference

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Genital herpes simplex virus infection

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Inhibiting sexual transmission of HIV-1 infection

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

21 January 2018

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21 January 2018

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21 January 2018

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Microbicides and other topical strategies to prevent vaginal transmission of HIV.

21 January 2018

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Microbicides: stopping HIV at the gate

21 January 2018

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The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission

21 January 2018

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Safety of single daily use for one week of C31G HEC gel in women.

21 January 2018

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A phase I comparative postcoital testing study of three concentrations of C31G.

21 January 2018

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Comparative safety evaluation of the candidate vaginal microbicide C31G

21 January 2018

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Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

21 January 2018

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Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States

21 January 2018

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Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants.

21 January 2018

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Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread

21 January 2018

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PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial

21 January 2018

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Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Evaluation of dendrimer SPL7013, a lead microbicide candidate against herpes simplex viruses

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Mandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entry

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Single and multiple exposure tolerance study of cellulose sulfate gel: a Phase I safety and colposcopy study.

21 January 2018

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Structural flexibility and functional valence of CD4-IgG2 (PRO 542): potential for cross-linking human immunodeficiency virus type 1 envelope spikes

21 January 2018

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Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Alpha-(1-3)- and alpha-(1-6)-D-mannose-specific plant lectins are markedly inhibitory to human immunodeficiency virus and cytomegalovirus infections in vitro

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

21 January 2018

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Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Synergistic in vitro antiretroviral activity of a humanized monoclonal anti-CD4 antibody (TNX-355) and enfuvirtide (T-20).

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

CD4 down-modulating compounds with potent anti-HIV activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

The CCR5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive HIV entry inhibitor

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

GlaxoSmithKline ends aplaviroc trials

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Pathogens use carbohydrates to escape immunity induced by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Current HIV treatment guidelines--an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Evaluation of oral tenofovir disoproxil fumarate and topical tenofovir GS-7340 to protect infant macaques against repeated oral challenges with virulent simian immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

HIV/AIDS. Prevention cocktails: combining tools to Stop HIV's spread

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Modulation of HIV-1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Intrinsic immunity: a front-line defense against viral attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Which topical microbicides for blocking HIV-1 transmission will work in the real world?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

HIV-1 Trafficking to the Dendritic Cell-T-Cell Infectious Synapse Uses a Pathway of Tetraspanin Sorting to the Immunological Synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.5.1.77

21 January 2018

Identifiers

DOI

10.1586/14787210.5.1.77

1 reference

20 June 2017

1 reference