Structural and dynamical features of inteins and implications on protein splicing. (Q30360932)

15 September 2017

Structural and dynamical features of inteins and implications on protein splicing. (English)

1 reference

15 September 2017

Neel H Shah

2

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David Cowburn

object named as

David Cowburn

series ordinal

4

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author name string

Ertan Eryilmaz

series ordinal

1

1 reference

15 September 2017

Tom W Muir

series ordinal

3

1 reference

15 September 2017

language of work or name

English

0 references

publication date

2 April 2014

1 reference

Journal of Biological Chemistry

15 September 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

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15 September 2017

289

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15 September 2017

21

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15 September 2017

14506-14511

1 reference

Naturally split inteins assemble through a "capture and collapse" mechanism

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Intermolecular domain swapping induces intein-mediated protein alternative splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Structural basis for protein trans-splicing by a bacterial intein-like domain--protein ligation without nucleophilic side chains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Extein residues play an intimate role in the rate-limiting step of protein trans-splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

A conserved threonine spring-loads precursor for intein splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Recent progress in intein research: from mechanism to directed evolution and applications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Mutual synergistic protein folding in split intein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

NMR and Crystal Structures of the Pyrococcus horikoshii RadA Intein Guide a Strategy for Engineering a Highly Efficient and Promiscuous Intein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Mechanisms and principles of N-linked protein glycosylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Highly efficient and more general cis- and trans-splicing inteins through sequential directed evolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split intein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

p K a Coupling at the Intein Active Site: Implications for the Coordination Mechanism of Protein Splicing with a Conserved Aspartate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Electronic structure of neighboring extein residue modulates intein C-terminal cleavage activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Spontaneous proton transfer to a conserved intein residue determines on-pathway protein splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Backbone dynamics and global effects of an activating mutation in minimized Mtu RecA inteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Branched intermediate formation stimulates peptide bond cleavage in protein splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Splicing of the mycobacteriophage Bethlehem DnaB intein: identification of a new mechanistic class of inteins that contain an obligate block F nucleophile.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Selection and Structure of Hyperactive Inteins: Peripheral Changes Relayed to the Catalytic Center

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Enzymatic transition states and dynamic motion in barrier crossing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Traceless protein splicing utilizing evolved split inteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Solution structure of DnaE intein from Nostoc punctiforme: structural basis for the design of a new split intein suitable for site-specific chemical modification

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

NMR structure of a KlbA intein precursor fromMethanococcus jannaschii

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Crystallographic and Mutational Studies of Mycobacterium tuberculosis recA Mini-inteins Suggest a Pivotal Role for a Highly Conserved Aspartate Residue

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

UCSF Chimera--a visualization system for exploratory research and analysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Protein splicing and related forms of protein autoprocessing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Structural insights into the protein splicing mechanism of PI-SceI

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Protein splicing of inteins and hedgehog autoproteolysis: structure, function, and evolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Compilation and analysis of intein sequences

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Protein splicing: an analysis of the branched intermediate and its resolution by succinimide formation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

The SEA module: a new extracellular domain associated with O-glycosylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031508

Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

The Thermococcus kodakaraensis Tko CDC21-1 intein activates its N-terminal splice junction in the absence of a conserved histidine by a compensatory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Distribution of split DnaE inteins in cyanobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Faster protein splicing with the Nostoc punctiforme DnaE intein using non-native extein residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Probing intein-catalyzed thioester formation by unnatural amino acid substitutions in the active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Protein splicing in the absence of an intein penultimate histidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Highly efficient proteintrans-splicing by a naturally split DnaE intein fromNostoc punctiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R113.540302

Protein Splicing: Characterization of the Aminosuccinimide Residue at the Carboxyl Terminus of the Excised Intervening Sequence

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24695731

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A genetic system yields self-cleaving inteins for bioseparations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24695731

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.R113.540302

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

24695731

1 reference