Emerging influenza viruses and the prospect of a universal influenza virus vaccine. (Q30372274)

21 June 2017

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title

Emerging influenza viruses and the prospect of a universal influenza virus vaccine. (English)

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21 June 2017

Florian Krammer

1

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publication date

2 March 2015

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21 June 2017

Biotechnology Journal

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21 June 2017

10

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21 June 2017

5

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21 June 2017

690-701

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Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

21 June 2017

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https://api.crossref.org/works/10.1002%2FBIOT.201400393

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Seroevidence for H5N1 influenza infections in humans: meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Highly pathogenic avian influenza A(H5N8) virus from waterfowl, South Korea, 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Highly pathogenic avian influenza virus (H5N8) in domestic poultry and its relationship with migratory birds in South Korea during 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A novel highly pathogenic H5N8 avian influenza virus isolated from a wild duck in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Novel reassortant influenza A(H5N8) viruses in domestic ducks, eastern China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Novel reassortant influenza A(H5N8) viruses, South Korea, 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Human infection with a novel avian-origin influenza A (H7N9) virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Role of poultry in the spread of novel H7N9 influenza virus in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Human infection with avian influenza A H6N1 virus: an epidemiological analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Origin and molecular characteristics of a novel 2013 avian influenza A(H6N1) virus causing human infection in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Origin and molecular characterization of the human-infecting H6N1 influenza virus in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

H6 influenza viruses pose a potential threat to human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Identification of an H6N6 swine influenza virus in southern China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Replication of avian influenza viruses in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Avian influenza A H10N8--a virus on the verge?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Expansion of genotypic diversity and establishment of 2009 H1N1 pandemic-origin internal genes in pigs in China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The M segment of the 2009 new pandemic H1N1 influenza virus is critical for its high transmission efficiency in the guinea pig model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The M segment of the 2009 pandemic influenza virus confers increased neuraminidase activity, filamentous morphology, and efficient contact transmissibility to A/Puerto Rico/8/1934-based reassortant viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Identification of H2N3 influenza A viruses from swine in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Why do influenza virus subtypes die out? A hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Vaccinate for the next H2N2 pandemic now.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Emergence of fatal avian influenza in New England harbor seals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A distinct lineage of influenza A virus from bats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

New world bats harbor diverse influenza A viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Safety and immunogenicity of two different doses of a Vero cell-derived, whole virus clade 2 H5N1 (A/Indonesia/05/2005) influenza vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The future of cell culture-based influenza vaccine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Clinical development of a Vero cell culture-derived seasonal influenza vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Synthetic generation of influenza vaccine viruses for rapid response to pandemics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A cell culture-derived MF59-adjuvanted pandemic A/H7N9 vaccine is immunogenic in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Recombinant protein vaccines produced in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Receptor specificity of influenza A H3N2 viruses isolated in mammalian cells and embryonated chicken eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Alternative influenza vaccines made by insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Development of influenza H7N9 virus like particle (VLP) vaccine: homologous A/Anhui/1/2013 (H7N9) protection and heterologous A/chicken/Jalisco/CPA1/2012 (H7N3) cross-protection in vaccinated mice challenged with H7N9 virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

An influenza A/H1N1/2009 hemagglutinin vaccine produced in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The emergence of H7N9 viruses: a chance to redefine correlates of protection for influenza virus vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Induction of broadly neutralizing H1N1 influenza antibodies by vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Prime-boost interval matters: a randomized phase 1 study to identify the minimum interval necessary to observe the H5 DNA influenza vaccine priming effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A live attenuated influenza A(H5N1) vaccine induces long-term immunity in the absence of a primary antibody response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Influenza virus hemagglutinin stalk-based antibodies and vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The annual production cycle for influenza vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Antibody recognition of a highly conserved influenza virus epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A common solution to group 2 influenza virus neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A highly conserved neutralizing epitope on group 2 influenza A viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Highly Conserved Protective Epitopes on Influenza B Viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Assessment of influenza virus hemagglutinin stalk-based immunity in ferrets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A universal influenza A vaccine based on the extracellular domain of the M2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Induction of virus-specific cytotoxic T lymphocytes as a basis for the development of broadly protective influenza vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Universal influenza virus vaccines: need for clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Hemagglutinin stalk-based universal vaccine constructs protect against group 2 influenza A viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

An H7N1 influenza virus vaccine induces broadly reactive antibody responses against H7N9 in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Influenza virus vaccine based on the conserved hemagglutinin stalk domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Design of Escherichia coli-expressed stalk domain immunogens of H1N1 hemagglutinin that protect mice from lethal challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Preparation of influenza virus subviral particles lacking the HA1 subunit of hemagglutinin: unmasking of cross-reactive HA2 determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Eliciting broadly protective antibody responses against influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Antibody breadth and protective efficacy are increased by vaccination with computationally optimized hemagglutinin but not with polyvalent hemagglutinin-based H5N1 virus-like particle vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A computationally optimized broadly reactive antigen (COBRA) based H5N1 VLP vaccine elicits broadly reactive antibodies in mice and ferrets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A computationally optimized hemagglutinin virus-like particle vaccine elicits broadly reactive antibodies that protect nonhuman primates from H5N1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Nanoclusters self-assembled from conformation-stabilized influenza M2e as broadly cross-protective influenza vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Preliminary assessment of the efficacy of a T-cell-based influenza vaccine, MVA-NP+M1, in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Coadministration of seasonal influenza vaccine and MVA-NP+M1 simultaneously achieves potent humoral and cell-mediated responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Safety and immunogenicity of multimeric-001--a novel universal influenza vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

In the shadow of hemagglutinin: a growing interest in influenza viral neuraminidase and its role as a vaccine antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Antigen-presenting B cells and helper T cells cooperatively mediate intravirionic antigenic competition between influenza A virus surface glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Induction of Partial Immunity to Influenza by a Neuraminidase-specific Vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Infection-permissive immunization with influenza virus neuraminidase prevents weight loss in infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Purified influenza A virus N2 neuraminidase vaccine is immunogenic and non-toxic in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Immunization with purified N1 and N2 influenza virus neuraminidases demonstrates cross-reactivity without antigenic competition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Analyzing swine sera for functional antibody titers against influenza A neuraminidase proteins using an enzyme-linked lectin assay (ELLA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Stability of neuraminidase in inactivated influenza vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

A monoclonal antibody targeting a highly conserved epitope in influenza B neuraminidase provides protection against drug resistant strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Universal anti-neuraminidase antibody inhibiting all influenza A subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

The 2009 pandemic H1N1 virus induces anti-neuraminidase (NA) antibodies that cross-react with the NA of H5N1 viruses in ferrets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Molecular basis for broad neuraminidase immunity: conserved epitopes in seasonal and pandemic H1N1 as well as H5N1 influenza viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Protection against a lethal H5N1 influenza challenge by intranasal immunization with virus-like particles containing 2009 pandemic H1N1 neuraminidase in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Human infection from avian-like influenza A (H1N1) viruses in pigs, China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Human infection with Eurasian avian-like influenza A(H1N1) virus, China

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Highly pathogenic avian influenza A(H7N3) virus in poultry workers, Mexico, 2012.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Influenza virus A (H10N7) in chickens and poultry abattoir workers, Australia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

Avian influenza A(H10N7) virus involvement in mass mortality of harbour seals (Phoca vitulina) in Sweden, March through October 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400393

21 January 2018

Identifiers

DOI

10.1002/BIOT.201400393

1 reference

21 June 2017

1 reference

PubMed ID

25728134