Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity. (Q30373502)

17 August 2017

Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity. (English)

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17 August 2017

7

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Daniela Vullo

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object named as

Daniela Vullo

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17 August 2017

Fatemeh Bootorabi

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17 August 2017

Janne Jänis

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17 August 2017

Jarkko Valjakka

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17 August 2017

Sari Isoniemi

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17 August 2017

Pirjo Vainiotalo

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17 August 2017

Abdul Waheed

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17 August 2017

William S Sly

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17 August 2017

Onni Niemelä

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17 August 2017

Seppo Parkkila

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17 August 2017

27 November 2008

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17 August 2017

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Alcoholic macrocytosis--is there a role for acetaldehyde and adducts?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

The plasma membrane carbonic anhydrase in murine hepatocytes identified as isozyme XIV.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Distribution of ethanol-induced protein adducts in vivo: relationship to tissue injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

An overview of the distribution and function of carbonic anhydrase in mammals.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Aldehyde-protein adducts in the liver as a result of ethanol-induced oxidative stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Identification of the 37-kd rat liver protein that forms an acetaldehyde adduct in vivo as delta 4-3-ketosteroid 5 beta-reductase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Acetaldehyde/protein interactions: are they involved in the pathogenesis of alcoholic liver disease?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Distribution of the carbonic anhydrase isoenzymes I, II, and VI in the human alimentary tract

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Detection of reduced acetaldehyde protein adducts using a unique monoclonal antibody

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Partial rescue of human carbonic anhydrase II frameshift mutation by ribosomal frameshift

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Human blood acetaldehyde (update 1992).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

A structural assignment for a stable acetaldehyde-lysine adduct.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Medical disorders of alcoholism.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Acetaldehyde adducts with hemoglobin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Clinical implications of acetaldehyde adducts with hemoglobin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Impaired acetaldehyde metabolism in patients with non-alcoholic liver disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Reaction of acetaldehyde with hemoglobin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Carbonic anhydrase II deficiency: diagnosis and carrier detection using differential enzyme inhibition and inactivation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Increased covalent binding of acetaldehyde to calmodulin in the presence of calcium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Immunohistochemical localization of carbonic anhydrase isoenzymes VI, II, and I in human parotid and submandibular glands

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Hemoglobin-acetaldehyde adducts in human volunteers following acute ethanol ingestion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

The chemistry of acetaldehyde-protein adducts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Modification of proteins and other biological molecules by acetaldehyde: adduct structure and functional significance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Reaction of acetaldehyde with human erythrocyte membrane proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Measurement of acetaldehyde: what levels occur naturally and in response to alcohol?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Recent advances in alcohol-induced adduct formation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Generation of aldehyde-derived protein modifications in ethanol-exposed heart.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Determination of hepatic acetaldehyde and its biphasic relationship to the ethanol concentration in rats.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605449

Crystal structure of human carbonic anhydrase C

26 November 2018

1 reference

12 December 2020

Elevated blood acetaldehyde in alcoholics with accelerated ethanol elimination

1 reference

12 December 2020

Hemoglobin-acetaldehyde adducts in human alcohol abusers

1 reference

12 December 2020

Immune responses to acetaldehyde-protein adducts: role in alcoholic liver disease

1 reference

12 December 2020

Production of antibodies that recognize the heterogeneity of immunoreactive sites in human hemoglobin chemically modified by acetaldehyde

1 reference

12 December 2020

Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation

1 reference

12 December 2020

The formation and stability of imidazolidinone adducts from acetaldehyde and model peptides. A kinetic study with implications for protein modification in alcohol abuse

1 reference

12 December 2020

Stable acetaldehyde adducts: structural characterization of acetaldehyde adducts of human hemoglobin N-terminal beta-globin chain peptides

1 reference

12 December 2020

Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption

1 reference

12 December 2020

A simplified micromethod for the determination of carbonic anhydrase and its inhibitors

1 reference

12 December 2020

Acetaldehyde adducts with proteins: binding of [14C]acetaldehyde to serum albumin

1 reference

12 December 2020

Covalent binding of acetaldehyde selectively inhibits the catalytic activity of lysine-dependent enzymes

1 reference

12 December 2020

Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo

1 reference

12 December 2020

Red blood cells: a new major modality for acetaldehyde transport from liver to other tissues

1 reference

12 December 2020

Acetaldehyde binding increases the catabolism of rat serum low-density lipoproteins

1 reference

12 December 2020

The interaction of acetaldehyde with tubulin

1 reference

12 December 2020

The functional implications of acetaldehyde binding to cell constituents

1 reference

12 December 2020

Covalent binding of acetaldehyde to tubulin: evidence for preferential binding to the alpha-chain

1 reference

12 December 2020

The binding of acetaldehyde to the active site of ribonuclease: alterations in catalytic activity and effects of phosphate

1 reference

12 December 2020

Covalent binding of acetaldehyde to proteins: participation of lysine residues

1 reference

12 December 2020

Formation of acetaldehyde adducts with ethanol-inducible P450IIE1 in vivo

1 reference

12 December 2020

Preferential covalent binding of acetaldehyde to the alpha-chain of purified rat liver tubulin

1 reference

12 December 2020

Covalent binding of acetaldehyde to type III collagen

1 reference

12 December 2020

Covalent interactions of acetaldehyde with the actin/microfilament system

1 reference

12 December 2020

Expression of testosterone-dependent enzyme, carbonic anhydrase III, and oxidative stress in experimental alcoholic liver disease

1 reference

12 December 2020

Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers

1 reference

12 December 2020

Evidence of acetaldehyde-protein adduct formation in rat brain after lifelong consumption of ethanol

1 reference

12 December 2020

Generation of protein adducts with malondialdehyde and acetaldehyde in muscles with predominantly type I or type II fibers in rats exposed to ethanol and the acetaldehyde dehydrogenase inhibitor cyanamide

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2091-9-32

1 reference

Dimensions Publication ID

17 August 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1471-2091-9-32

1 reference

17 August 2017

PubMed publication ID

19036170

1 reference