Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model (Q30395163)

24 February 2018

title

Efficacy of the broad-spectrum antiviral compound BCX4430 against Zika virus in cell culture and in a mouse model (English)

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24 February 2018

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11

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Justin G Julander

1

object named as

Justin G Julander

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PMCID

5215849

24 February 2018

Venkatraman Siddharthan

2

object named as

Venkatraman Siddharthan

1 reference

24 February 2018

14

John D Morrey

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24 February 2018

Joe Evans

3

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24 February 2018

Ray Taylor

4

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24 February 2018

Kelsey Tolbert

5

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24 February 2018

Chad Apuli

6

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24 February 2018

Jason Stewart

7

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24 February 2018

Preston Collins

8

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24 February 2018

Makda Gebre

9

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24 February 2018

Skot Neilson

10

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24 February 2018

Young-Min Lee

12

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24 February 2018

William P Sheridan

13

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24 February 2018

Y S Babu

15

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24 February 2018

language of work or name

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9 November 2016

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24 February 2018

number of pages

9

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based on heuristic

inferred from page(s)

published in

Antiviral Research

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24 February 2018

volume

137

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24 February 2018

page(s)

14-22

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24 February 2018

on focus list of Wikimedia project

WikiProject Zika Corpus

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cites work

Guillain-Barré Syndrome During Ongoing Zika Virus Transmission — Puerto Rico, January 1–July 31, 2016

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Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection

20 June 2018

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Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

20 June 2018

1 reference

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Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215849

Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice

20 June 2018

1 reference

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The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

20 June 2018

1 reference

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A Susceptible Mouse Model for Zika Virus Infection

20 June 2018

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Zika virus damages the human placental barrier and presents marked fetal neurotropism

20 June 2018

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Zika virus: An update on epidemiology, pathology, molecular biology, and animal model

20 June 2018

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Positive IgM for Zika virus in the cerebrospinal fluid of 30 neonates with microcephaly in Brazil

20 June 2018

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Characterization of Lethal Zika Virus Infection in AG129 Mice

20 June 2018

1 reference

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Clinical features and neuroimaging (CT and MRI) findings in presumed Zika virus related congenital infection and microcephaly: retrospective case series study

20 June 2018

1 reference

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Zika Virus and Birth Defects — Reviewing the Evidence for Causality

20 June 2018

1 reference

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A Mouse Model of Zika Virus Pathogenesis

20 June 2018

1 reference

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Guillain-Barré syndrome associated with the Zika virus outbreak in Brazil

20 June 2018

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Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

20 June 2018

1 reference

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Characterization of a Novel Murine Model to Study Zika Virus

20 June 2018

1 reference

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Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

20 June 2018

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Emergence of Congenital Zika Syndrome: Viewpoint From the Front Lines

20 June 2018

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Zika Virus Associated with Microcephaly

20 June 2018

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Zika virus: a previously slow pandemic spreads rapidly through the Americas

20 June 2018

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Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy

20 June 2018

1 reference

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BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model

20 June 2018

1 reference

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HIV protease inhibitor use during pregnancy is associated with decreased progesterone levels, suggesting a potential mechanism contributing to fetal growth restriction

20 June 2018

1 reference

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Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

20 June 2018

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A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain

20 June 2018

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Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling

20 June 2018

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Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog

20 June 2018

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Neurological suppression of diaphragm electromyographs in hamsters infected with West Nile virus

20 June 2018

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Persistent West Nile Virus Associated with a Neurological Sequela in Hamsters Identified by Motor Unit Number Estimation

20 June 2018

1 reference

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Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106

20 June 2018

1 reference

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C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection

20 June 2018

1 reference

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Identification of active antiviral compounds against a New York isolate of West Nile virus

20 June 2018

1 reference

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Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215849

Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215849

An infection-based model of neurodevelopmental damage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215849

New mouse model for dengue virus vaccine testing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215849

Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice

20 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27838352

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Maternal viral load, CD4 cell count and vertical transmission of HIV-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27838352

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.ANTIVIRAL.2016.11.003

1 reference

24 February 2018

PMCID

5215849

1 reference

24 February 2018

PubMed ID

27838352

1 reference

24 February 2018