Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell (Q30406039)

21 August 2017

Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell (English)

1 reference

21 August 2017

0 references

1 reference

Sheng Wu

1

1 reference

21 August 2017

Sara Divall

2

1 reference

21 August 2017

Amanda Nwaopara

3

1 reference

21 August 2017

Sally Radovick

4

1 reference

21 August 2017

Fredric Wondisford

5

1 reference

21 August 2017

Chemyong Ko

6

1 reference

21 August 2017

Andrew Wolfe

7

1 reference

21 August 2017

language of work or name

English

0 references

publication date

30 December 2013

1 reference

21 August 2017

1 reference

21 August 2017

63

1 reference

21 August 2017

1270-1282

1 reference

21 August 2017

4

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

21 August 2017

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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20 June 2018

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Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Molecular mechanisms of insulin resistance in polycystic ovary syndrome

20 June 2018

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The intraovarian actions of estrogen receptor-alpha are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad

20 June 2018

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20 June 2018

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Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1.

20 June 2018

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Insulin Augmentation of 17α-Hydroxylase Activity Is Mediated by Phosphatidyl Inositol 3-Kinase But Not Extracellular Signal-Regulated Kinase-1/2 in Human Ovarian Theca Cells

20 June 2018

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20 June 2018

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Interactive stimulation by luteinizing hormone and insulin of the steroidogenic acute regulatory (StAR) protein and 17alpha-hydroxylase/17,20-lyase (CYP17) genes in porcine theca cells

20 June 2018

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Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: common and distinct features

20 June 2018

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Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome

20 June 2018

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20 June 2018

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Adrenal glands of mouse and rat do not synthesize androgens

20 June 2018

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20 June 2018

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Ovarian theca cells in follicular function

26 November 2018

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Obesity and poor reproductive outcome: the potential role of the endometrium.

26 November 2018

1 reference

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PCOS according to the Rotterdam consensus criteria: Change in prevalence among WHO-II anovulation and association with metabolic factors

26 November 2018

1 reference

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Dietary-induced obesity and hypothalamic infertility in female DBA/2J mice

26 November 2018

1 reference

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Changes in Leydig cell gene expression during development in the mouse

26 November 2018

1 reference

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Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis.

26 November 2018

1 reference

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Luteinizing hormone receptor, steroidogenesis acute regulatory protein, and steroidogenic enzyme messenger ribonucleic acids are overexpressed in thecal and granulosa cells from polycystic ovaries

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

An autoregulatory process for androgen production in rat thecal-interstitial cells

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Altered expression of insulin and insulin-like growth factor-I receptors in follicular and stromal compartments of polycystic ovaries.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Insulin stimulates androgen accumulation in incubations of human ovarian stroma and theca.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Steroid-protein interactions II.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Hyperinsulinemia and human chorionic gonadotropin synergistically promote the growth of ovarian follicular cysts in rats

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3964497

Insulin as a regulator of androgen biosynthesis by cultured rat ovarian cells: cellular mechanism(s) underlying physiological and pharmacological hormonal actions

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379345

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Insulin action in human granulosa cells from normal and polycystic ovaries is mediated by the insulin receptor and not the type-I insulin-like growth factor receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379345

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nitric oxide reverses prostaglandin-induced inhibition in ovarian progesterone secretion in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24379345

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB13-1514

1 reference

21 August 2017

1 reference

21 August 2017

1 reference