Inositol, glycogen, insulin, and six nobelists (Q30413667)

16 August 2017

Inositol, glycogen, insulin, and six nobelists (English)

1 reference

16 August 2017

Joseph Larner

1

1 reference

PMC publication ID

3636915

16 August 2017

language of work or name

English

0 references

publication date

20 March 2013

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

288

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16 August 2017

17

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16 August 2017

12313-12324

1 reference

Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Uncoupling between insulin and release of a D-chiro-inositol-containing inositolphosphoglycan mediator of insulin action in obese women With polycystic ovary syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Synthesis of C-glycoside analogues of beta-galactosamine-(1-->4)-3-O-methyl-D-chiro-inositol and assay as activator of protein phosphatases PDHP and PP2Calpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

d- chiro-Inositol is absorbed but not synthesised in rodents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

ENZYMES IN A GLYCOGEN STORAGE MYOPATHY.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Insulin-mediated effect on the activity of UDPG-glycogen transglucosylase of muscle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Inositol dehydrogenase from Aerobacter aerogenes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

The renal excretion of inositol by normal and diabetic rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

The renal excretion of inositol in normal and diabetic human beings

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Isolation, structure, synthesis, and bioactivity of a novel putative insulin mediator. A galactosamine chiro-inositol pseudo-disaccharide Mn2+ chelate with insulin-like activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Phosphoinositol glycan derived mediators and insulin resistance. Prospects for diagnosis and therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

In vivo chiro-inositol metabolism in the rat: a defect in chiro-inositol synthesis from myo-inositol and an increased incorporation of chiro-[3H]inositol into phospholipid in the Goto-Kakizaki (G.K) rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Urinary myo-inositol-to-chiro-inositol ratios and insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Chiroinositol deficiency and insulin resistance. III. Acute glycogenic and hypoglycemic effects of two inositol phosphoglycan insulin mediators in normal and streptozotocin-diabetic rats in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Krebs EG: Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Insulin mediators: structure and formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphate contains galactosamine and D-chiroinositol.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Molecular cloning of rat type 2C (IA) protein phosphatase mRNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Low urinary chiro-inositol excretion in non-insulin-dependent diabetes mellitus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Structural studies on rabbit muscle glycogen synthase. I. Subunit composition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Generation by Insulin of a Chemical Mediator That Controls Protein Phosphorylation and Dephosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Hormonal effects on fat cell adenosine 3′,5′-monophosphate dependent protein kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Reversible inhibition of cyclic AMP-dependent protein kinase by insulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Rabbit skeletal muscle glycogen synthase. II. Enzyme phosphorylation state and effector concentrations as interacting control parameters

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X113.471177

Chronic treatment with d-chiro-inositol prevents autonomic and somatic neuropathy in STZ-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X113.471177

Insulin resistance in human preeclamptic placenta is mediated by serine phosphorylation of insulin receptor substrate-1 and -2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X113.471177

On the requirement for diphosphopyridine nucleotide in the aerobic metabolism of pyruvate by brain tissue.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3636915

Influence Of Epinephrine and Insulin on Uridine Diphosphate Glucose-α-Glucan Transferase and Phosphorylase in Muscle

26 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.X113.471177

Antihyperglycemic effects of 3-O-methyl-D-chiro-inositol and D-chiro-inositol associated with manganese in streptozotocin diabetic rats

21 January 2018

1 reference

12 December 2020

Action of amylo-1,6-glucosidase and phosphorylase on glycogen and amylopectin

1 reference

12 December 2020

Purification and properties of glycogen synthase I from skeletal muscle: Two kinetic forms

1 reference

12 December 2020

Insulin mediators in man: effects of glucose ingestion and insulin resistance

1 reference

12 December 2020

Manganese-induced hypoglycaemia

1 reference

12 December 2020

STUDIES ON UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE. IV. PURIFICATION AND CHARACTERIZATION OF TWO FORMS FROM RABBIT SKELETAL MUSCLE

1 reference

12 December 2020

Participation of histidine in catalytic activity of intestinal carbohydrases

1 reference

12 December 2020

STUDIES ON UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE. III. INTERCONVERSION OF TWO FORMS OF MUSCLE UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE BY A PHOSPHORYLATION-DEPHOSPHORYLATION REACTION SEQUENCE

1 reference

12 December 2020

Uridine diphosphate glucose: alpha-1,4-glucan alpha-4-glucosyltransferase in heart. Two forms of the enzyme, interconversion reactions and properties

1 reference

12 December 2020

Gastrointestinal digestion of starch. I. The action of oligo-1,6-glucosidase on branched saccharides

1 reference

12 December 2020

STUDIES ON UDPG: ALPHA-1,4-GLUCAN ALPHA-4-GLUCOSYLTRANSFERASE. VII. CONVERSION OF THE ENZYME FROM GLUCOSE-6-PHOSPHATE-DEPENDENT TO INDEPENDENT FORM IN LIVER

1 reference

12 December 2020

Levels of activity of the enzymes of the glycogen cycle in rat tissues

1 reference

12 December 2020

The action of branching enzymes on outer chains of glycogen

1 reference

12 December 2020

THE NATURE OF THE ANTI-ALOPECIA FACTOR

1 reference

12 December 2020

Structure of glycogens and amylopectins. II. Analysis by stepwise enzymatic degradation

1 reference

12 December 2020

STUDIES ON UDPG-ALPHA-GLUCAN TRANSGLUCOSYLASE. V. TWO FORMS OF THE ENZYME IN DOG SKELETAL MUSCLE AND THEIR INTERCONVERSION

1 reference

12 December 2020

A proteolytic mechanism for the action of insulin via oligopeptide mediator formation

1 reference

12 December 2020

The synthesis of inositol in the immature rat and chick embryo

1 reference

12 December 2020

Uridinediphosphate glucose pyrophosphorylase from skeletal muscle

1 reference

12 December 2020

Genetic and hormonal control of glycogen metabolism

1 reference

12 December 2020

Pyruvate dehydrogenase activation in adipocyte mitochondria by an insulin-generated mediator from muscle

1 reference

12 December 2020

Purification and Characterization of Mg2+-Dependent Glycogen Synthase Phosphatase (Phosphoprotein Phosphatase IA) from Rat Liver

1 reference

12 December 2020

Insulin-stimulated glycogen formation in rat diaphragm. Levels of tissue intermediates in short-time experiments

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.X113.471177

1 reference

16 August 2017

1 reference

PMC publication ID

3636915

16 August 2017

PubMed publication ID

23515311

1 reference

PMC publication ID

3636915