Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells (Q30416277)

19 August 2017

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells (English)

1 reference

19 August 2017

1 reference

Jonghyeob Lee

1

1 reference

19 August 2017

Takuya Sugiyama

2

1 reference

19 August 2017

Yinghua Liu

3

1 reference

19 August 2017

Jing Wang

4

1 reference

19 August 2017

Xueying Gu

5

1 reference

19 August 2017

Ji Lei

6

1 reference

19 August 2017

James F Markmann

7

1 reference

19 August 2017

Satsuki Miyazaki

8

1 reference

19 August 2017

Jun-Ichi Miyazaki

9

1 reference

19 August 2017

Gregory L Szot

10

1 reference

19 August 2017

Rita Bottino

11

1 reference

19 August 2017

Seung K Kim

12

1 reference

19 August 2017

language of work or name

English

0 references

publication date

19 November 2013

1 reference

19 August 2017

1 reference

19 August 2017

2

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19 August 2017

e00940

1 reference

Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Generating β cells from stem cells-the story so far

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Deconstructing pancreas developmental biology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Self-renewing endodermal progenitor lines generated from human pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Purified human pancreatic duct cell culture conditions defined by serum-free high-content growth factor screening

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Diabetes mellitus and the β cell: the last ten years

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Direct lineage conversions: unnatural but useful?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

MicroRNA-mediated conversion of human fibroblasts to neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Pancreas organogenesis: from bud to plexus to gland

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

The insulin secretory granule as a signaling hub.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Deconstructing pancreas development to reconstruct human islets from pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Rfx6 directs islet formation and insulin production in mice and humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Pancreas vs. islet transplantation: a call on the future

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Direct cell reprogramming is a stochastic process amenable to acceleration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Chronology of islet differentiation revealed by temporal cell labeling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Exocytosis of insulin: in vivo maturation of mouse endocrine pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Isolation and functional characterization of murine prostate stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

The pancreatic ductal epithelium serves as a potential pool of progenitor cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

In vitro cultivation of human islets from expanded ductal tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Constructing adenoviral vectors by using the circular form of the adenoviral genome cloned in a cosmid and the Cre-loxP recombination system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Extra-insular beta cells associated with ductules are frequent in adult human pancreas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3826580

Overexpression of metallothionein in pancreatic beta-cells reduces streptozotocin-induced DNA damage and diabetes

20 June 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Differentiation of CD133-positive pancreatic cells into insulin-producing islet-like cell clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

A multipotent progenitor domain guides pancreatic organogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00940

Isolation, culture, and characterization of human pancreatic duct cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24252877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differentiation of Affinity-Purified Human Pancreatic Duct Cells to -Cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24252877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.00940

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

24252877

1 reference