Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. (Q30416998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851703%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells (English)

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9 February 2020

0 references

5

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9 February 2020

author name string

Kellie M Breen

1

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9 February 2020

Varykina G Thackray

2

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9 February 2020

Tracy Hsu

3

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9 February 2020

Rachel A Mak-McCully

4

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9 February 2020

Pamela L Mellon

6

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publication date

31 July 2012

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9 February 2020

published in

Molecular Endocrinology

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9 February 2020

volume

26

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9 February 2020

issue

10

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9 February 2020

page(s)

1716-1731

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Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.

9 February 2020

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Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression

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Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line

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Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope

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Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements.

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Androgen suppression of GnRH-stimulated rat LHbeta gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region

20 June 2018

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AR suppresses transcription of the LHbeta subunit by interacting with steroidogenic factor-1.

20 June 2018

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Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (egr-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-beta gene promoter: an integral role for SF-1.

20 June 2018

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Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1.

20 June 2018

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Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription

20 June 2018

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Steroidogenic factor-1 and early growth response protein 1 act through two composite DNA binding sites to regulate luteinizing hormone beta-subunit gene expression.

20 June 2018

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The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Dual role of glucocorticoids in regulation of pituitary content and secretion of gonadotropins.

20 June 2018

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Effect of Stress on the Activity of the Hypothalamic-Pituitary-Gonadal Axis: Peripheral and Central Mechanisms1

20 June 2018

1 reference

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Regulatory Peptides of the Hypothalamus

20 June 2018

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Endocrine basis for disruptive effects of cortisol on preovulatory events

20 June 2018

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The influence of 17beta-oestradiol on corticotrophin-releasing hormone induced suppression of luteinising hormone pulses and the role of CRH in hypoglycaemic stress-induced suppression of pulsatile LH secretion in the female rat.

26 November 2018

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Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress

26 November 2018

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Differential effects of repeated restraint stress on pulsatile lutenizing hormone secretion in female Fischer, Lewis and Wistar rats.

26 November 2018

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Progesterone receptor, estrogen receptor alpha, and the type II glucocorticoid receptor are coexpressed in the same neurons of the ovine preoptic area and arcuate nucleus: a triple immunolabeling study

26 November 2018

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Effect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep

26 November 2018

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26 November 2018

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In Vivo and in Vitro Studies on the Effect of Adrenocorticotropic Hormone or Cortisol on the Pituitary Response to Gonadotropin Releasing Hormone

26 November 2018

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Does cortisol acting via the type II glucocorticoid receptor mediate suppression of pulsatile luteinizing hormone secretion in response to psychosocial stress?

26 November 2018

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12 December 2020

Transcriptional regulation of the GnRH receptor gene by glucocorticoids

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12 December 2020

Control of the Preovulatory Release of Luteinizing Hormone By Steroids in the Mouse*

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12 December 2020

Stress-induced inhibition of reproductive functions: role of endogenous corticotropin-releasing factor

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12 December 2020

Dexamethasone reduces the postcastration gonadotropin rise in women

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12 December 2020

Effect of short-term elevations in plasma cortisol concentration on LH secretion in prepubertal gilts

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12 December 2020

Effect of treatment with cortisol in vivo on secretion of gonadotropins in vitro

1 reference

12 December 2020

Differential effects of in vitro glucocorticoids on luteinizing hormone and follicle-stimulating hormone secretion: dependence on sex of pituitary donor

1 reference

12 December 2020

Suppression of the hypothalamic-pituitary-ovarian axis in normal women by glucocorticoids

1 reference

12 December 2020

The antiglucocorticoid, RU486, attenuates stress-induced decreases in plasma-luteinizing hormone concentrations in male rats

1 reference

12 December 2020

Glucocorticoid repression of gonadotropin-releasing hormone gene expression and secretion in morphologically distinct subpopulations of GT1-7 cells

1 reference

12 December 2020

Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice

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12 December 2020

Identifiers

DOI

10.1210/ME.2011-1327

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851703%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851703%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851703%20AND%20SRC:MED&resulttype=core&format=json