Salsalate attenuates free fatty acid-induced microvascular and metabolic insulin resistance in humans (Q30426185)

3 November 2017

Salsalate attenuates free fatty acid-induced microvascular and metabolic insulin resistance in humans (English)

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3 November 2017

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ChEBI release 2020-05-28

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Weidong Chai

1

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3 November 2017

Jia Liu

2

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3 November 2017

Linda A Jahn

3

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3 November 2017

Dale E Fowler

4

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3 November 2017

Eugene J Barrett

5

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3 November 2017

Zhenqi Liu

6

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3 November 2017

language of work or name

English

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publication date

26 May 2011

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3 November 2017

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3 November 2017

34

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3 November 2017

7

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3 November 2017

1634-1638

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

3 November 2017

start time

1 September 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Free fatty acids induce insulin resistance in both cardiac and skeletal muscle microvasculature in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Salsalate improves glycemia and inflammatory parameters in obese young adults

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Insulin at physiological concentrations increases microvascular perfusion in human myocardium

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Inflammation and insulin resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

IKK-beta links inflammation to obesity-induced insulin resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Prevention of fat-induced insulin resistance by salicylate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRbeta/IRS-1 and Akt.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Salicylates increase insulin secretion in healthy obese subjects

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Mechanisms of the kinetic defect in insulin action in obesity and NIDDM.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3120177

Effect of insulin on human aortic endothelial nitric oxide synthase

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21617098

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21617098

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DC10-2345

1 reference

3 November 2017

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3 November 2017

1 reference