Principles and practices of integrating genotoxicity evaluation into routine toxicology studies: a pharmaceutical industry perspective (Q30431698)

21 June 2017

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title

Principles and practices of integrating genotoxicity evaluation into routine toxicology studies: a pharmaceutical industry perspective (English)

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21 June 2017

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Krishna G

1

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21 June 2017

Urda G

series ordinal

2

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21 June 2017

Theiss J

series ordinal

3

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21 June 2017

publication date

1 January 1998

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Environmental and Molecular Mutagenesis

21 June 2017

published in

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volume

32

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21 June 2017

issue

2

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21 June 2017

page(s)

115-120

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The suitability of rat peripheral blood in suchronic studies for the micronucleus assay

21 June 2017

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21 January 2018

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Determination of genotoxic and other effects in mice following short term repeated-dose and subchronic inhalation exposure to phosphine

21 January 2018

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Purpose and guidelines for toxicokinetic studies within the National Toxicology Program

21 January 2018

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Induction of micronuclei by benzene in B6C3F1 mice: retrospective analysis of peripheral blood smears from the NTP carcinogenesis bioassay.

21 January 2018

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The use of pharmacokinetics as an interpretive and predictive tool in chemical toxicology testing and risk assessment: a position paper on the appropriate use of pharmacokinetics in chemical toxicology

21 January 2018

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Quantification of hprt gene deletions mediated by illegitimate V(D)J recombination in peripheral blood cells of humans

21 January 2018

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The in vivo erythrocyte micronucleus test: measurement at steady state increases assay efficiency and permits integration with toxicity studies

21 January 2018

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The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program

21 January 2018

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Safety screening of drugs in cancer therapy

21 January 2018

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Micronuclei induced in peripheral blood of E mu-PIM-1 transgenic mice by chronic oral treatment with 2-acetylaminofluorene or benzene but not with diethyl-nitrosamine or 1,2-dichloroethane

21 January 2018

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Use of acridine orange in: flow cytometric evaluation of erythropoietic cytotoxicity

21 January 2018

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Use of acridine orange in: flow cytometric assessment of micronuclei induction

21 January 2018

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The in vivo rat micronucleus test: integration with a 14-day study

21 January 2018

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The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

21 January 2018

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Induction of micronuclei in rat bone marrow and peripheral blood following acute and subchronic administration of azathioprine

21 January 2018

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A direct comparison of mouse and rat bone marrow and blood as target tissues in the micronucleus assay

21 January 2018

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Concurrent analysis of cytogenetic damage in vivo: A multiple endpoint‐multiple tissue approach

21 January 2018

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Simultaneous micronucleus and chromosome aberration assessment in the rat

21 January 2018

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Integration of cytogenetic assays with toxicology studies

21 January 2018

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Induction of chromosome aberrations in lymphocytes of mice after subchronic exposure to benzene

21 January 2018

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The persistence of micronuclei in peripheral blood erythrocytes: detection of chronic chromosome breakage in mice

21 January 2018

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The persistence of micronucleated erythrocytes in the peripheral circulation of normal and splenectomized Fischer 344 rats: implications for cytogenetic screening

21 January 2018

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Comparative cytogenetic analysis of bone marrow damage induced in male B6C3F1 mice by multiple exposures to gaseous 1,3-butadiene

21 January 2018

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Effects of ethylene on micronucleus formation in the bone marrow of rats and mice following four weeks of inhalation exposure

21 January 2018

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Phenolphthalein: induction of micronucleated erythrocytes in mice

21 January 2018

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21 January 2018

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10.1002/(SICI)1098-2280(1998)32:2<115::AID-EM6>3.0.CO;2-6

21 January 2018

Identifiers

DOI

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21 June 2017

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