Critical functions for c-Myb at three checkpoints during thymocyte development (Q30433753)

21 June 2017

title

Critical functions for c-Myb at three checkpoints during thymocyte development (English)

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21 June 2017

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Thorsten Buch

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Klaus Rajewsky

object named as

Klaus Rajewsky

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author name string

Timothy P Bender

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21 June 2017

Christopher S Kremer

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Manfred Kraus

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21 June 2017

language of work or name

English

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publication date

13 June 2004

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21 June 2017

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21 June 2017

volume

5

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issue

7

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21 June 2017

page(s)

721-729

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Intrathymic maturation of murine T lymphocytes from CD8+ precursors

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cites work

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Pleiotropic changes controlled by the pre-T-cell receptor

21 January 2018

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T-cell development and the CD4-CD8 lineage decision

21 January 2018

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The myb gene family in cell growth, differentiation and apoptosis

21 January 2018

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

21 January 2018

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Differential expression of the amv gene in human hematopoietic cells

21 January 2018

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A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

21 January 2018

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Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation.

21 January 2018

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Interleukin-2 induction of T-cell G1 progression and c-myb expression

21 January 2018

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c-Myb is essential for early T cell development

21 January 2018

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Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences

21 January 2018

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T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination

21 January 2018

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

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c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock

21 January 2018

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Enhancer control of local accessibility to V(D)J recombinase

21 January 2018

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Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

21 January 2018

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The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes

21 January 2018

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CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

21 January 2018

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Requirement for RORgamma in thymocyte survival and lymphoid organ development

21 January 2018

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Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

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c-Myb regulates the proliferation of immature thymocytes following beta-selection

21 January 2018

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c-Myb binds to a sequence in the proximal region of the RAG-2 promoter and is essential for promoter activity in T-lineage cells

21 January 2018

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Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement

21 January 2018

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Gene segment selection in V(D)J recombination: accessibility and beyond

21 January 2018

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Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene

21 January 2018

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A dominant interfering Myb mutant causes apoptosis in T cells

21 January 2018

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Bclx regulates the survival of double-positive thymocytes

21 January 2018

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Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

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Expression of the CD4 gene requires a Myb transcription factor

21 January 2018

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Negative regulation of CD4 gene expression by a HES-1-c-Myb complex

21 January 2018

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Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

21 January 2018

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Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain

21 January 2018

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Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

21 January 2018

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T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

21 January 2018

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Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

21 January 2018

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Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation

21 January 2018

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7 January 2021

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

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7 January 2021

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

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7 January 2021

A nonredundant role for the adapter protein Shc in thymic T cell development

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7 January 2021

Identifiers

DOI

10.1038/NI1085

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21 June 2017

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