Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men (Q30445095)

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28 January 2020

title

Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men (English)

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28 January 2020

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5

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28 January 2020

author name string

Kimberly A Burton

1

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28 January 2020

Deborah A McDermott

2

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28 January 2020

David Wilkes

3

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28 January 2020

Melissa N Poulsen

4

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28 January 2020

Marc Goldstein

6

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28 January 2020

Craig T Basson

7

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28 January 2020

G Stanley McKnight

8

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28 January 2020

publication date

25 May 2006

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28 January 2020

published in

Molecular Endocrinology

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28 January 2020

volume

20

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28 January 2020

issue

10

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28 January 2020

page(s)

2504-2513

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Inactivation of the mouse adenylyl cyclase 3 gene disrupts male fertility and spermatozoon function

28 January 2020

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Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice

20 June 2018

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Sperm-specific protein kinase A catalytic subunit Calpha2 orchestrates cAMP signaling for male fertility

20 June 2018

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Mutation of perinatal myosin heavy chain associated with a Carney complex variant

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Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect

20 June 2018

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Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility.

20 June 2018

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Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysio

20 June 2018

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Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit (PRKAR1A) in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity, and schwannomas" (Carney complex)

20 June 2018

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Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo

20 June 2018

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The expanding family of CREB/CREM transcription factors that are involved with spermatogenesis

20 June 2018

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Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function

20 June 2018

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Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex

20 June 2018

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The unique catalytic subunit of sperm cAMP-dependent protein kinase is the product of an alternative Calpha mRNA expressed specifically in spermatogenic cells

20 June 2018

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Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex.

20 June 2018

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Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

20 June 2018

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Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA.

20 June 2018

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Expression of a nonmyristylated variant of the catalytic subunit of protein kinase A during male germ-cell development.

20 June 2018

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Deletion of type IIalpha regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization.

20 June 2018

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Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase

20 June 2018

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Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits

20 June 2018

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Premature translation of protamine 1 mRNA causes precocious nuclear condensation and arrests spermatid differentiation in mice

20 June 2018

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Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.

20 June 2018

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A unique mRNA species for a regulatory subunit of cAMP-dependent protein kinase is specifically induced in haploid germ cells

20 June 2018

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20 June 2018

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20 June 2018

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Post-transcriptional regulation of cAMP-dependent protein kinase activity by cAMP in GH3 pituitary tumor cells. Evidence for increased degradation of catalytic subunit in the presence of cAMP.

20 June 2018

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20 June 2018

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20 June 2018

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26 November 2018

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26 November 2018

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26 November 2018

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Involvement of protein kinase A in the phosphorylation of spermatidal protein TP2 and its effect on DNA condensation

26 November 2018

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Subunits of cyclic adenosine 3',5'-monophosphate-dependent protein kinase show differential and distinct expression patterns during germ cell differentiation: alternative polyadenylation in germ cells gives rise to unique smaller-sized mRNA species.

26 November 2018

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Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis

26 November 2018

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Fine structure of the spermatic granuloma of the rat vas deferens following vasectomy

26 November 2018

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12 December 2020

Experimental production of spermatic granuloma in Balb/c mice

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12 December 2020

P2 protamines are phosphorylated in vitro by protein kinase C, whereas P1 protamines prefer cAMP-dependent protein kinase. A comparative study of five mammalian species

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12 December 2020

Identification of a novel genetic locus for familial cardiac myxomas and Carney complex

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12 December 2020

Identifiers

DOI

10.1210/ME.2006-0060

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16728532%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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28 January 2020

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