Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo (Q30454428)

10 August 2017

Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo (English)

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10 August 2017

W H Martin

1

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10 August 2017

D J Hoover

2

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10 August 2017

S J Armento

3

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10 August 2017

I A Stock

4

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10 August 2017

R K McPherson

5

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10 August 2017

D E Danley

6

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10 August 2017

R W Stevenson

7

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10 August 2017

E J Barrett

8

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10 August 2017

J L Treadway

9

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10 August 2017

language of work or name

English

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publication date

1 February 1998

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

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10 August 2017

95

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10 August 2017

4

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10 August 2017

1776-1781

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Enzymatic studies of hepatic fragments; application to the classification of glycogenoses

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Hepatic gluconeogenic fluxes and glycogen turnover during fasting in humans. A stable isotope study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Glucose production, recycling, and gluconeogenesis in normals and diabetics: a mass isotopomer [U-13C]glucose study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Contributions of gluconeogenesis to glucose production in the fasted state

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Hepatic glucose metabolism and insulin resistance in NIDDM and obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Actions of the novel antidiabetic agent englitazone in rat hepatocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Effects of C-1-substituted glucose analogue on the activation states of glycogen synthase and glycogen phosphorylase in rat hepatocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

The family of glycogen phosphorylases: structure and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Simultaneous synthesis and degradation of rat liver glycogen. An in vivo nuclear magnetic resonance spectroscopic study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

An engineered liver glycogen phosphorylase with AMP allosteric activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

New Pharmacological Approaches to Therapy of NIDDM

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Role of liver in pathophysiology of NIDDM

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Pathogenesis of NIDDM. A balanced overview

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Role of liver and muscle in type II diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

The nucleotide sequence of rat liver glycogen phosphorylase cDNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

An improved assay for nanomole amounts of inorganic phosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Enhanced muscle glucose metabolism after exercise in the rat: the two phases

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19188

Kinetic mechanism of phosphorylase a. I. Initial velocity studies

26 November 2018

1 reference

12 December 2020

The regulation of glycogen phosphorylase alpha by nucleotide derivatives. Kinetic and x-ray crystallographic studies

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12 December 2020

Synergistic regulation of phosphorylase a by glucose and caffeine

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12 December 2020

Regulation of the dephosphorylation of glycogen phosphorylase a and synthase b by glucose and caffeine in isolated hepatocytes

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12 December 2020

Analysis of an allosteric binding site: the nucleoside inhibitor site of phosphorylase alpha

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12 December 2020

Glucose uptake and insulin sensitivity in rat muscle: changes during 3-96 weeks of age

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12 December 2020

Purification of glycogen phosphorylase isozymes by metal-affinity chromatography

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12 December 2020

Insulin and glucose suppress hepatic glycogenolysis by distinct enzymatic mechanisms

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12 December 2020

Glycogen: its mode of formation and contribution to hepatic glucose output in postabsorptive humans

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12 December 2020

A new technique for isolating and culturing human hepatocytes from whole or split livers not used for transplantation

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12 December 2020

Effects of novel analogues of D-glucose on glycogen phosphorylase activities in crude extracts of liver and skeletal muscle.

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12 December 2020

The effect of caffeine and caffeine analogs on rat liver phosphorylase a activity

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12 December 2020

Laboratory animals exhibiting obesity and diabetes syndromes

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12 December 2020

Identifiers

DOI

10.1073/PNAS.95.4.1776

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10 August 2017

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10 August 2017

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