Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis (Q30465168)

19 October 2017

Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis (English)

1 reference

19 October 2017

3

Gwen Lomberk

1 reference

19 October 2017

Dominique Thabut

1

1 reference

19 October 2017

Chittaranjan Routray

2

1 reference

19 October 2017

Uday Shergill

4

1 reference

19 October 2017

Kevin Glaser

5

1 reference

19 October 2017

Robert Huebert

6

1 reference

19 October 2017

Leena Patel

7

1 reference

19 October 2017

Tetyana Masyuk

8

1 reference

19 October 2017

Boris Blechacz

9

1 reference

19 October 2017

Andrew Vercnocke

10

1 reference

19 October 2017

Erik Ritman

11

1 reference

19 October 2017

Richard Ehman

12

1 reference

19 October 2017

Raul Urrutia

13

1 reference

19 October 2017

Vijay Shah

14

1 reference

19 October 2017

language of work or name

English

0 references

publication date

26 June 2011

1 reference

19 October 2017

1 reference

19 October 2017

54

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19 October 2017

2

1 reference

19 October 2017

573-585

1 reference

Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib: a clinical and pharmacologic review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib targets dysregulated Rho kinase expression and portal hypertension in rats with secondary biliary cirrhosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Tie2 is tied at the cell-cell contacts and to extracellular matrix by angiopoietin-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Sorafenib in advanced hepatocellular carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Magnetic resonance imaging of hepatic fibrosis: emerging clinical applications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Signaling and functions of angiopoietin-1 in vascular protection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Endothelial/pericyte interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Molecular regulation of vessel maturation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Three-dimensional imaging of vasculature and parenchyma in intact rodent organs with X-ray micro-CT.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Magnetic resonance elastography by direct visualization of propagating acoustic strain waves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145033

Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis.

20 June 2018

1 reference

Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

21 January 2018

1 reference

Magnetic resonance elastography: non-invasive mapping of tissue elasticity.

21 January 2018

1 reference

Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation.

21 January 2018

1 reference

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

21 January 2018

1 reference

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats

21 January 2018

1 reference

Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

21 January 2018

1 reference

Strengthening tight junctions of retinal microvascular endothelial cells by pericytes under normoxia and hypoxia involving angiopoietin-1 signal way.

21 January 2018

1 reference

Sp1 binding activity increases in activated Ito cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21567441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21567441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/HEP.24427

1 reference

19 October 2017

1 reference

19 October 2017

1 reference