Transcriptional targeting of glioblastoma by diphtheria toxin-A driven by both H19 and IGF2-P4 promoters. (Q30467807)

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31 January 2020

title

Transcriptional targeting of glioblastoma by diphtheria toxin-A driven by both H19 and IGF2-P4 promoters (English)

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31 January 2020

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Doron Amit

1

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31 January 2020

Imad J Matouk

2

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31 January 2020

Iris Lavon

3

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31 January 2020

Tatiana Birman

4

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31 January 2020

Jenifer Galula

5

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31 January 2020

Rasha Abu-Lail

6

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31 January 2020

Tamar Schneider

7

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31 January 2020

Tali Siegal

8

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31 January 2020

Abraham Hochberg

9

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31 January 2020

Yakov Fellig

10

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31 January 2020

publication date

6 April 2012

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International Journal of Clinical and Experimental Medicine

31 January 2020

published in

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31 January 2020

volume

5

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31 January 2020

issue

2

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31 January 2020

page(s)

124-135

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Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences

31 January 2020

cites work

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20 June 2018

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The IGFR1 inhibitor NVP-AEW541 disrupts a pro-survival and pro-angiogenic IGF-STAT3-HIF1 pathway in human glioblastoma cells

20 June 2018

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20 June 2018

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Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas

20 June 2018

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The H19 non-coding RNA is essential for human tumor growth

20 June 2018

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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

20 June 2018

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Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells

20 June 2018

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Convection-enhanced delivery of targeted toxins for malignant glioma

20 June 2018

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H19 expression in hepatic metastases from a range of human carcinomas

20 June 2018

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Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

20 June 2018

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The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma

20 June 2018

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Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.

20 June 2018

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Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development

20 June 2018

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Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas

20 June 2018

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Diphtheria Toxin−Epidermal Growth Factor Fusion Protein and Pseudomonas Exotoxin−Interleukin 13 Fusion Protein Exert Synergistic Toxicity against Human Glioblastoma Multiforme Cells

20 June 2018

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Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences

20 June 2018

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20 June 2018

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The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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IGF2 but not H19 shows loss of imprinting in human glioma.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors

20 June 2018

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Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein

20 June 2018

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Identification and initial characterization of a fourth leader exon and promoter of the human IGF-II gene.

20 June 2018

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The human ASM (adult skeletal muscle) gene: expression and chromosomal assignment to 11p15

20 June 2018

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Expression of diphtheria toxin A-chain in mature B-cells: a potential approach to therapy of B-lymphoid malignancy

20 June 2018

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Expression of insulin-like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry

20 June 2018

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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

20 June 2018

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Glioblastoma and cerebral microvascular endothelial cell migration in response to tumor-associated growth factors.

26 November 2018

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Use of H19 regulatory sequences for targeted gene therapy in cancer

26 November 2018

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Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals

26 November 2018

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Transcriptional regulation and biological significance of the insulin like growth factor II gene.

26 November 2018

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Relaxation of Imprinting of Human Insulin-like Growth Factor II Gene,IGF2,in Sporadic Breast Carcinomas

26 November 2018

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Insulin-like growth factors (IGF) enhance three-dimensional (3D) growth of human glioblastomas.

26 November 2018

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Differential expression of the human, mouse and rat IGF-II genes.

26 November 2018

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Parental genomic imprinting of the human IGF2 gene

26 November 2018

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12 December 2020

Regulatory sequences of H19 and IGF2 genes in DNA-based therapy of colorectal rat liver metastases

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12 December 2020

Promoter-specific IGF2 imprinting status and its plasticity during human liver development

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12 December 2020

Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice

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12 December 2020

Genomic imprinting of IGF2 and H19 in human meningiomas

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22567173%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference