To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front (Q30480454)

12 August 2017

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front (English)

1 reference

12 August 2017

Zachary A Knight

3

0 references

author name string

Alexandra Van Keymeulen

1

1 reference

12 August 2017

Kit Wong

2

1 reference

12 August 2017

Cedric Govaerts

4

1 reference

12 August 2017

Klaus M Hahn

5

1 reference

12 August 2017

Kevan M Shokat

6

1 reference

12 August 2017

Henry R Bourne

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

24 July 2006

1 reference

12 August 2017

9

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

12 August 2017

174

1 reference

12 August 2017

437-445

1 reference

12 August 2017

3

1 reference

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Spatiotemporal dynamics of RhoA activity in migrating cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

A microtubule-dependent zone of active RhoA during cleavage plane specification

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Neutrophil microtubules suppress polarity and enhance directional migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Regulation of PTEN by Rho small GTPases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Concentric zones of active RhoA and Cdc42 around single cell wounds

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Biology of the p21-activated kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Eukaryotic chemotaxis: distinctions between directional sensing and polarization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cellular control of actin nucleation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Cell motility: can Rho GTPases and microtubules point the way?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Localized Rac activation dynamics visualized in living cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Ras family GTPases control growth of astrocyte processes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

p110δ, a novel phosphoinositide 3-kinase in leukocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa

14 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Centrosome localization determines neuronal polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

PTEN regulates motility but not directionality during leukocyte chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200604113

Regulation of breast cancer cell chemotaxis by the phosphoinositide 3-kinase p110delta.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064239

Microtubule capture: IQGAP and CLIP-170 expand the repertoire

26 November 2018

1 reference

12 December 2020

Orientation of chemotactic cells and growth cones: models and mechanisms

1 reference

12 December 2020

A membrane-permeant ester of phosphatidylinositol 3,4, 5-trisphosphate (PIP(3)) is an activator of human neutrophil migration

1 reference

12 December 2020

Stimulation of human neutrophils by chemotactic factors is associated with the activation of phosphatidylinositol 3-kinase gamma

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200604113

1 reference

12 August 2017

1 reference

12 August 2017

1 reference