Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules (Q30481754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18427107%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules (English)

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6 January 2020

1 reference

1

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6 January 2020

4

Emil R Unanue

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6 January 2020

author name string

Anish Suri

series ordinal

2

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6 January 2020

Mark J Miller

series ordinal

3

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6 January 2020

language of work or name

English

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publication date

21 April 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18427107%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 January 2020

published in

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6 January 2020

volume

105

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6 January 2020

page(s)

6121-6126

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6 January 2020

issue

16

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In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.

6 January 2020

cites work

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Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

20 June 2018

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Diabetes is predicted by the beta cell level of autoantigen

20 June 2018

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Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse

20 June 2018

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Visualizing dendritic cell networks in vivo

20 June 2018

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A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.

20 June 2018

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Insulin cell mass is altered in Csf1op/Csf1op macrophage-deficient mice

20 June 2018

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Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

20 June 2018

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Fatal attraction: chemokines and type 1 diabetes

20 June 2018

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Two-photon tissue imaging: seeing the immune system in a fresh light

20 June 2018

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Perspective on antigen processing and presentation.

20 June 2018

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Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

20 June 2018

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beta-Cell death during progression to diabetes

20 June 2018

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Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

20 June 2018

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Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody.

20 June 2018

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Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody

20 June 2018

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The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages of endocrine organs

20 June 2018

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Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

20 June 2018

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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

20 June 2018

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In situ analysis of pancreatic islets in rats developing diabetes. Appearance of nonendocrine cells with surface MHC class II antigens and cytoplasmic insulin immunoreactivity

20 June 2018

1 reference

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Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

20 June 2018

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Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

20 June 2018

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Prolongation of Islet Allograft Survival Following in Vitro Culture (24°C) and a Single Injection of ALS

20 June 2018

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A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis.

20 June 2018

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Dendritic Cells Process and Present Antigens Across A Range of Maturation States

21 January 2018

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In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes

21 January 2018

1 reference

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Thermodynamics of Antigen-antibody Binding using Specific Anti-lysozyme Antibodies

21 January 2018

1 reference

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Reversal of diabetes by allogenic islet transplantation without immunosuppression.

21 January 2018

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Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells

26 November 2018

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12 December 2020

Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice

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12 December 2020

Islet filtration: a simple and rapid new purification procedure that avoids ficoll and improves islet mass and function

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12 December 2020

Threshold detection of self-antigen/MHC class II complexes formed in vivo: constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice

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12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

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12 December 2020

Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice

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12 December 2020

Relationship between beta cell injury and antigen presentation in NOD mice

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12 December 2020

Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes

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12 December 2020

Quantitative analysis of the T cell repertoire that escapes negative selection

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0801973105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18427107%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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6 January 2020

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