Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains. (Q30482005)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557288%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains (English)

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1 November 2019

1

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1 November 2019

Jonathon Howard

series ordinal

2

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1 November 2019

author name string

W O Hancock

series ordinal

1

1 reference

15 August 2017

J Howard

series ordinal

2

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 November 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557288%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557288%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

96

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1 November 2019

page(s)

13147-13152

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1 November 2019

issue

23

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Congruent docking of dimeric kinesin and ncd into three-dimensional electron cryomicroscopy maps of microtubule-motor ADP complexes.

1 November 2019

cites work

1 reference

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A processive single-headed motor: kinesin superfamily protein KIF1A.

20 June 2018

1 reference

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Role of the kinesin neck region in processive microtubule-based motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Processivity of the motor protein kinesin requires two heads

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Kinesin and dynein superfamily proteins and the mechanism of organelle transport

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

The crystal structure of dimeric kinesin and implications for microtubule-dependent motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Molecular motors: the natural economy of kinesin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Mechanics of single kinesin molecules measured by optical trapping nanometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Coupling of kinesin steps to ATP hydrolysis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Kinesin hydrolyses one ATP per 8-nm step

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Movements of truncated kinesin fragments with a short or an artificial flexible neck

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

The movement of kinesin along microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Directional loading of the kinesin motor molecule as it buckles a microtubule.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Direct observation of single kinesin molecules moving along microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Motor proteins 1: kinesins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Chemomechanical cycle of kinesin differs from that of myosin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Direct observation of kinesin stepping by optical trapping interferometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Drosophila kinesin motor domain extending to amino acid position 392 is dimeric when expressed in Escherichia coli.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Kinesin follows the microtubule's protofilament axis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Pathway of processive ATP hydrolysis by kinesin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Organelle transport and sorting in axons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

The force generated by a single kinesin molecule against an elastic load

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Is myosin a "back door" enzyme?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Kinesin ATPase: rate-limiting ADP release

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Bead movement by single kinesin molecules studied with optical tweezers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Evidence that the head of kinesin is sufficient for force generation and motility in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Evidence that the stalk of Drosophila kinesin heavy chain is an alpha-helical coiled coil

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Kinesin undergoes a 9 S to 6 S conformational transition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Movement of microtubules by single kinesin molecules

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Kinetic mechanism of a monomeric kinesin construct.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Alternating site mechanism of the kinesin ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Kinesin's tail domain is an inhibitory regulator of the motor domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Nucleotide-dependent conformations of the kinesin dimer interacting with microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Kinesin takes one 8-nm step for each ATP that it hydrolyzes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23915

Highly processive microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Failure of a single-headed kinesin to track parallel to microtubule protofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Single kinesin molecules studied with a molecular force clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.23.13147

Force and velocity measured for single kinesin molecules

21 January 2018

1 reference

12 December 2020

Kinetic mechanism of kinesin motor domain

1 reference

12 December 2020

Weak and strong states of kinesin and ncd

1 reference

12 December 2020

Interacting head mechanism of microtubule-kinesin ATPase

1 reference

12 December 2020

Monomeric kinesin head domains hydrolyze multiple ATP molecules before release from a microtubule

1 reference

12 December 2020

Influence of the kinesin neck domain on dimerization and ATPase kinetics

1 reference

12 December 2020

Pathway of ATP hydrolysis by monomeric and dimeric kinesin

1 reference

12 December 2020

A model of the microtubule-kinesin complex based on electron cryomicroscopy and X-ray crystallography

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.23.13147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557288%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557288%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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