Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples (Q30483107)

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English	Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples	scientific article

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scholarly article

1 reference

Europe PubMed Central

15 October 2017

Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples (English)

1 reference

Europe PubMed Central

15 October 2017

1 reference

based on heuristic

inferred from title

author name string

Lamei Chen

1

1 reference

Europe PubMed Central

15 October 2017

Christopher Lee

2

1 reference

Europe PubMed Central

15 October 2017

publication date

31 May 2006

1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

1

1 reference

Europe PubMed Central

15 October 2017

14

1 reference

Europe PubMed Central

15 October 2017

https://scigraph.springernature.com/pub.10.1186/1745-6150-1-14

0 references

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Evidence for Positive Epistasis in HIV-1

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Insights into saquinavir resistance in the G48V HIV-1 protease: quantum calculations and molecular dynamic simulations

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Update of the drug resistance mutations in HIV-1: 2004.

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HIV-1 subtype distribution and the problem of drug resistance

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HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance and a potential new target site for drugs

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Positive selection detection in 40,000 human immunodeficiency virus (HIV) type 1 sequences automatically identifies drug resistance and positive fitness mutations in HIV protease and reverse transcriptase

1 reference

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Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments

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Molecular characteristics of human immunodeficiency virus type 1 subtype C viruses from KwaZulu-Natal, South Africa: implications for vaccine and antiretroviral control strategies

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Combining mutations in HIV-1 protease to understand mechanisms of resistance

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Human immunodeficiency virus type 1 reverse-transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population

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Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations

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20 June 2018

Structural implications of drug-resistant mutants of HIV-1 protease: high-resolution crystal structures of the mutant protease/substrate analogue complexes

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20 June 2018

Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy

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20 June 2018

Molecular cloning and biological characterization of full-length HIV-1 subtype C from Botswana

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20 June 2018

Analysis of covariation in an SH3 domain sequence alignment: applications in tertiary contact prediction and the design of compensating hydrophobic core substitutions

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20 June 2018

Retracing the evolutionary pathways of human immunodeficiency virus type 1 resistance to protease inhibitors: virus fitness in the absence and in the presence of drug

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20 June 2018

Codon-substitution models for heterogeneous selection pressure at amino acid sites

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20 June 2018

Correlations among amino acid sites in bHLH protein domains: an information theoretic analysis

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20 June 2018

Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1.

1 reference

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20 June 2018

Coevolving protein residues: maximum likelihood identification and relationship to structure.

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20 June 2018

Structural comparison of major histocompatibility complex class I molecules and homology modelling of five distinct human leukocyte antigen-A alleles

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20 June 2018

Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors

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20 June 2018

Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays.

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20 June 2018

Unbiased estimation of the rates of synonymous and nonsynonymous substitution

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20 June 2018

Correlated mutations and residue contacts in proteins

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Viral dynamics in human immunodeficiency virus type 1 infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523337

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Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy

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Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

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Impact of frequent natural polymorphisms at the protease gene on the in vitro susceptibility to protease inhibitors in HIV-1 non-B subtypes

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26 November 2018

Multidrug Resistance to HIV-1 Protease Inhibition Requires Cooperative Coupling between Distal Mutations

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26 November 2018

A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523337

26 November 2018

Correlated mutation analyses on very large sequence families

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1523337

26 November 2018

Guidelines for using antiretroviral agents among HIV-infected adults and adolescents. Recommendations of the Panel on Clinical Practices for Treatment of HIV.

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Baseline human immunodeficiency virus type 1 phenotype, genotype, and RNA response after switching from long-term hard-capsule saquinavir to indinavir or soft-gel-capsule saquinavir in AIDS clinical trials group protocol 333.

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Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples.

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Complete mutagenesis of the HIV-1 protease

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection and reduction of evolutionary noise in correlated mutation analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16737543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for detecting positive selection at single amino acid sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16737543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of a novel method for the identification of coevolving protein residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/16737543

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1745-6150-1-14

1 reference

Europe PubMed Central

15 October 2017

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1 reference

Europe PubMed Central

15 October 2017

1 reference

Europe PubMed Central

15 October 2017

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