TRPA1 acts as a cold sensor in vitro and in vivo (Q30485737)

18 August 2017

TRPA1 acts as a cold sensor in vitro and in vivo (English)

1 reference

18 August 2017

Kelvin Y Kwan

5

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Karel Talavera

Karel Talavera

2

0 references

Rudi Vennekens

Rudi Vennekens

6

0 references

Thomas Voets

Thomas Voets

8

0 references

Bernd Nilius

7

Bernd Nilius

1 reference

18 August 2017

Yuji Karashima

1

1 reference

18 August 2017

Wouter Everaerts

3

1 reference

18 August 2017

Annelies Janssens

4

1 reference

18 August 2017

language of work or name

English

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publication date

14 January 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

106

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18 August 2017

4

1 reference

18 August 2017

1273-1278

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TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Neuronal TRP channels: thermometers, pathfinders and life-savers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Cold sensitivity of recombinant TRPA1 channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

The menthol receptor TRPM8 is the principal detector of environmental cold

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Attenuated cold sensitivity in TRPM8 null mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TRPM8 is required for cold sensation in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Transient receptor potential channel A1 is directly gated by calcium ions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Direct activation of the ion channel TRPA1 by Ca2+.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TRP channel activation by reversible covalent modification

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Transient receptor potential ion channels as participants in thermosensation and thermoregulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Heat activation of TRPM5 underlies thermal sensitivity of sweet taste

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Specificity of cold thermotransduction is determined by differential ionic channel expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Animal models of nociception.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

TREK-1 is a heat-activated background K(+) channel

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Visualizing cold spots: TRPM8-expressing sensory neurons and their projections.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Bimodal action of menthol on the transient receptor potential channel TRPA1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633575

An innovative cold tail-flick test: the cold ethanol tail-flick test

26 November 2018

1 reference

12 December 2020

A novel type of cold-sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli

1 reference

12 December 2020

Many cold sensitive peripheral neurons of the mouse do not express TRPM8 or TRPA1

1 reference

12 December 2020

Emergence of Functional Sensory Subtypes as Defined by Transient Receptor Potential Channel Expression

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0808487106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference